A Drop of Trouble: Uncovering the Systemic Adverse Effects of Topical Pilocarpine

Topical ophthalmic medications are frequently prescribed by eye care professionals, including optometrists and nurses with specialized training. However, these medications can lead to systemic side effects, particularly in elderly patients who may have multiple underlying health issues. We report th...

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Main Authors: Mariya Farooqui, Madhuri Venigalla, Malleswari Medikonda, Vandana Jagdish Thakur
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:Delhi Journal of Ophthalmology
Subjects:
Online Access:https://journals.lww.com/10.4103/DLJO.DLJO_179_24
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author Mariya Farooqui
Madhuri Venigalla
Malleswari Medikonda
Vandana Jagdish Thakur
author_facet Mariya Farooqui
Madhuri Venigalla
Malleswari Medikonda
Vandana Jagdish Thakur
author_sort Mariya Farooqui
collection DOAJ
description Topical ophthalmic medications are frequently prescribed by eye care professionals, including optometrists and nurses with specialized training. However, these medications can lead to systemic side effects, particularly in elderly patients who may have multiple underlying health issues. We report the case of a 70-year-old male who underwent YAG laser peripheral iridotomy in both eyes. Shortly after the procedure, he exhibited symptoms consistent with a myocardial infarction. In view of thorough investigations showing normal results, this incident suggests that the systemic absorption of pilocarpine eye drops may have contributed to his clinical presentation.
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institution Matheson Library
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language English
publishDate 2025-04-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Delhi Journal of Ophthalmology
spelling doaj-art-2b52d4bc5fc34d0a8c152d6fa2f579232025-07-04T06:13:16ZengWolters Kluwer Medknow PublicationsDelhi Journal of Ophthalmology0972-02002454-27842025-04-0135213113610.4103/DLJO.DLJO_179_24A Drop of Trouble: Uncovering the Systemic Adverse Effects of Topical PilocarpineMariya FarooquiMadhuri VenigallaMalleswari MedikondaVandana Jagdish ThakurTopical ophthalmic medications are frequently prescribed by eye care professionals, including optometrists and nurses with specialized training. However, these medications can lead to systemic side effects, particularly in elderly patients who may have multiple underlying health issues. We report the case of a 70-year-old male who underwent YAG laser peripheral iridotomy in both eyes. Shortly after the procedure, he exhibited symptoms consistent with a myocardial infarction. In view of thorough investigations showing normal results, this incident suggests that the systemic absorption of pilocarpine eye drops may have contributed to his clinical presentation.https://journals.lww.com/10.4103/DLJO.DLJO_179_24laser peripheral iridotomynausea and vomitingpilocarpinesystemic toxicity
spellingShingle Mariya Farooqui
Madhuri Venigalla
Malleswari Medikonda
Vandana Jagdish Thakur
A Drop of Trouble: Uncovering the Systemic Adverse Effects of Topical Pilocarpine
Delhi Journal of Ophthalmology
laser peripheral iridotomy
nausea and vomiting
pilocarpine
systemic toxicity
title A Drop of Trouble: Uncovering the Systemic Adverse Effects of Topical Pilocarpine
title_full A Drop of Trouble: Uncovering the Systemic Adverse Effects of Topical Pilocarpine
title_fullStr A Drop of Trouble: Uncovering the Systemic Adverse Effects of Topical Pilocarpine
title_full_unstemmed A Drop of Trouble: Uncovering the Systemic Adverse Effects of Topical Pilocarpine
title_short A Drop of Trouble: Uncovering the Systemic Adverse Effects of Topical Pilocarpine
title_sort drop of trouble uncovering the systemic adverse effects of topical pilocarpine
topic laser peripheral iridotomy
nausea and vomiting
pilocarpine
systemic toxicity
url https://journals.lww.com/10.4103/DLJO.DLJO_179_24
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