Development of approaches for studying the biodistribution of a bicistronic therapeutic plasmid construct in the mouse body
Relevance. The use of gene therapy drugs for the treatment of genetic diseases and stimulation of regeneration processes is lengthy and involves repeated injections, which may lead to increased dissemination of gene therapy constructs from the injection site and undesirable ectopic expression of gro...
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Main Authors: | S. S. Dzhauari, M. N. Karagyaur, V. Yu. Balabanyan, M. N. Skryabina, A. L. Primak, D. V. Stambolsky |
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Format: | Article |
Language: | Russian |
Published: |
LLC “Publisher OKI”
2022-07-01
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Series: | Фармакокинетика и Фармакодинамика |
Subjects: | |
Online Access: | https://www.pharmacokinetica.ru/jour/article/view/318 |
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