FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE)
The reaction of formylation by Vilsmeier - Haack was held. The effect of excess phosphorus oxychloride in the direction of the reaction. Optimal conditions were conducting formylation reaction to obtain a single compound with a high yield. The result of the reaction product mixture was conducted chr...
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| Format: | Article |
| Language: | Russian |
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LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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| Series: | Разработка и регистрация лекарственных средств |
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| Online Access: | https://www.pharmjournal.ru/jour/article/view/323 |
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| _version_ | 1839586772132036608 |
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| author | E. S. Ofitserova A. A. Shklyarenko I. P. Yakovlev E. V. Fedorova |
| author_facet | E. S. Ofitserova A. A. Shklyarenko I. P. Yakovlev E. V. Fedorova |
| author_sort | E. S. Ofitserova |
| collection | DOAJ |
| description | The reaction of formylation by Vilsmeier - Haack was held. The effect of excess phosphorus oxychloride in the direction of the reaction. Optimal conditions were conducting formylation reaction to obtain a single compound with a high yield. The result of the reaction product mixture was conducted chromatographic separation on a column packed with silica gel 60 Silica. |
| format | Article |
| id | doaj-art-2a1b3136a5604a25915dba9302455e9f |
| institution | Matheson Library |
| issn | 2305-2066 2658-5049 |
| language | Russian |
| publishDate | 2019-01-01 |
| publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
| record_format | Article |
| series | Разработка и регистрация лекарственных средств |
| spelling | doaj-art-2a1b3136a5604a25915dba9302455e9f2025-08-03T19:23:53ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-0101112114323FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE)E. S. Ofitserova0A. A. Shklyarenko1I. P. Yakovlev2E. V. Fedorova3Federal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State Chemical-Pharmaceutical Academy" of the Ministry of Health of the Russian FederationFederal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State Chemical-Pharmaceutical Academy" of the Ministry of Health of the Russian FederationFederal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State Chemical-Pharmaceutical Academy" of the Ministry of Health of the Russian FederationFederal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State Chemical-Pharmaceutical Academy" of the Ministry of Health of the Russian FederationThe reaction of formylation by Vilsmeier - Haack was held. The effect of excess phosphorus oxychloride in the direction of the reaction. Optimal conditions were conducting formylation reaction to obtain a single compound with a high yield. The result of the reaction product mixture was conducted chromatographic separation on a column packed with silica gel 60 Silica.https://www.pharmjournal.ru/jour/article/view/323formylationvilsmeier - haack reagentnucleophilic substitution |
| spellingShingle | E. S. Ofitserova A. A. Shklyarenko I. P. Yakovlev E. V. Fedorova FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE) Разработка и регистрация лекарственных средств formylation vilsmeier - haack reagent nucleophilic substitution |
| title | FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE) |
| title_full | FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE) |
| title_fullStr | FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE) |
| title_full_unstemmed | FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE) |
| title_short | FORMYLATION OF 2-(METHYLTHIO)PYRIMDINE-4,6-DIOL IN THE REACTIO CONDITIONS OF VILSMEIER-HAAK (SHORT MESSAGE) |
| title_sort | formylation of 2 methylthio pyrimdine 4 6 diol in the reactio conditions of vilsmeier haak short message |
| topic | formylation vilsmeier - haack reagent nucleophilic substitution |
| url | https://www.pharmjournal.ru/jour/article/view/323 |
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