Comparative effects of combustible cigarette versus electronic cigarette exposures on KRAS mutant lung cancer promotion

Comparative effects of combustible cigarette versus electronic cigarette exposures on KRAS mutant lung cancer promotion

Despite the emerging public health concern related to the use of electronic cigarette vapors (ECV), its impact on lung cancer is poorly understood. We assessed the effect of ECV on lung tumorigenesis in a mouse model of lung adenocarcinoma. Mice were exposed to either room air, combustible cigarette...

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Bibliographic Details
Main Authors: Walter V. Velasco, Maria T. Grimaldo, Nastaran Karimi, Michael J. Clowers, Avantika Krishna, Ranran Wu, Rahmah Ejaz, Bo Yuan, Segundo del Aguila, Iman Bouchelkia, Javier Eduardo Moreno Barragan, Katherine E. Larsen, Yasmina Rezai, Farbod Khalaj, Kyler Mitra, Carlos Reyna Rodriguez, Ricardo Millares, Angelica Baca de Anda, Susana Castro-Pando, Umesh C. Karandikar, Joseph F. Petrosino, Florencia McAllister, Humam Kadara, Edwin J. Ostrin, Johannes F. Fahrmann, Kristi Louise Hoffman, Seyed Javad Moghaddam
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Lung cancer
Cigarette smoke
Electronic cigarette
Kras
Microbiome
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558625000648
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