Efficacy of buccal piroxicam infiltration and inferior alveolar nerve block in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical trial

ObjectivesThis randomized clinical trial aimed to assess the effectiveness of buccal infiltration with piroxicam on the anesthetic efficacy of inferior alveolar nerve block (IANB) with buccal infiltration in irreversible pulpitis, with pain assessed using the Heft-Parker visual analogue scale (HP-VA...

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Main Authors: Saurav Paul, Sridevi Nandamuri, Aakrati Raina, Mukta Bansal
Format: Article
Language:English
Published: Korean Academy of Conservative Dentistry 2021-02-01
Series:Restorative Dentistry & Endodontics
Subjects:
Online Access:http://rde.ac/upload/pdf/rde-46-e9.pdf
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author Saurav Paul
Sridevi Nandamuri
Aakrati Raina
Mukta Bansal
author_facet Saurav Paul
Sridevi Nandamuri
Aakrati Raina
Mukta Bansal
author_sort Saurav Paul
collection DOAJ
description ObjectivesThis randomized clinical trial aimed to assess the effectiveness of buccal infiltration with piroxicam on the anesthetic efficacy of inferior alveolar nerve block (IANB) with buccal infiltration in irreversible pulpitis, with pain assessed using the Heft-Parker visual analogue scale (HP-VAS).Materials and MethodsThis study included 56 patients with irreversible pulpitis in mandibular molars, randomly distributed between 2 groups (n = 28). After evaluating the initial pain score with the HP-VAS, each patient received IANB followed by buccal infiltration of 2% lignocaine with adrenaline (1:80,000). Five minutes later, the patients in groups 1 and 2 were given buccal infiltration with 40 mg/2 mL of piroxicam or normal saline, respectively. An access opening procedure (AOP) was performed 15 minutes post-IANB once the individual showed signs of lip numbness as well as 2 negative responses to electric pulp testing. The HP-VAS was used to grade the patient's pain during caries removal (CR), AOP, and working length measurement (WLM). Successful anesthesia was identified either by the absence of pain or slight pain through CR, AOP, and WLM, with no requirement of a further anesthetic dose. A statistical analysis was done using the Shapiro-Wilk and Mann-Whitney U tests.ResultsThe piroxicam group presented a significantly lower (p < 0.05) mean pain score than the saline group during AOP.ConclusionsBuccal infiltration with piroxicam enhanced the efficacy of anesthesia with IANB and buccal infiltration with lignocaine in patients with irreversible pulpitis.
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spelling doaj-art-28e5ccd5f1094e7daf30d1893055ef1a2025-07-03T04:19:22ZengKorean Academy of Conservative DentistryRestorative Dentistry & Endodontics2234-76582234-76662021-02-01461e910.5395/rde.2021.46.e91004Efficacy of buccal piroxicam infiltration and inferior alveolar nerve block in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical trialSaurav Paul0Sridevi Nandamuri1Aakrati Raina2Mukta Bansal3Department of Conservative Dentistry and Endodontics, Rama Dental College, Hospital and Research Centre, Kanpur, Uttar Pradesh, IndiaDepartment of Conservative Dentistry and Endodontics, Rama Dental College, Hospital and Research Centre, Kanpur, Uttar Pradesh, IndiaDepartment of Conservative Dentistry and Endodontics, Rama Dental College, Hospital and Research Centre, Kanpur, Uttar Pradesh, IndiaDepartment of Conservative Dentistry and Endodontics, Rama Dental College, Hospital and Research Centre, Kanpur, Uttar Pradesh, IndiaObjectivesThis randomized clinical trial aimed to assess the effectiveness of buccal infiltration with piroxicam on the anesthetic efficacy of inferior alveolar nerve block (IANB) with buccal infiltration in irreversible pulpitis, with pain assessed using the Heft-Parker visual analogue scale (HP-VAS).Materials and MethodsThis study included 56 patients with irreversible pulpitis in mandibular molars, randomly distributed between 2 groups (n = 28). After evaluating the initial pain score with the HP-VAS, each patient received IANB followed by buccal infiltration of 2% lignocaine with adrenaline (1:80,000). Five minutes later, the patients in groups 1 and 2 were given buccal infiltration with 40 mg/2 mL of piroxicam or normal saline, respectively. An access opening procedure (AOP) was performed 15 minutes post-IANB once the individual showed signs of lip numbness as well as 2 negative responses to electric pulp testing. The HP-VAS was used to grade the patient's pain during caries removal (CR), AOP, and working length measurement (WLM). Successful anesthesia was identified either by the absence of pain or slight pain through CR, AOP, and WLM, with no requirement of a further anesthetic dose. A statistical analysis was done using the Shapiro-Wilk and Mann-Whitney U tests.ResultsThe piroxicam group presented a significantly lower (p < 0.05) mean pain score than the saline group during AOP.ConclusionsBuccal infiltration with piroxicam enhanced the efficacy of anesthesia with IANB and buccal infiltration with lignocaine in patients with irreversible pulpitis.http://rde.ac/upload/pdf/rde-46-e9.pdfanesthesiabuccal infiltrationinferior alveolar nerve blockirreversible pulpitislignocainepiroxicam
spellingShingle Saurav Paul
Sridevi Nandamuri
Aakrati Raina
Mukta Bansal
Efficacy of buccal piroxicam infiltration and inferior alveolar nerve block in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical trial
Restorative Dentistry & Endodontics
anesthesia
buccal infiltration
inferior alveolar nerve block
irreversible pulpitis
lignocaine
piroxicam
title Efficacy of buccal piroxicam infiltration and inferior alveolar nerve block in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical trial
title_full Efficacy of buccal piroxicam infiltration and inferior alveolar nerve block in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical trial
title_fullStr Efficacy of buccal piroxicam infiltration and inferior alveolar nerve block in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical trial
title_full_unstemmed Efficacy of buccal piroxicam infiltration and inferior alveolar nerve block in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical trial
title_short Efficacy of buccal piroxicam infiltration and inferior alveolar nerve block in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical trial
title_sort efficacy of buccal piroxicam infiltration and inferior alveolar nerve block in patients with irreversible pulpitis a prospective double blind randomized clinical trial
topic anesthesia
buccal infiltration
inferior alveolar nerve block
irreversible pulpitis
lignocaine
piroxicam
url http://rde.ac/upload/pdf/rde-46-e9.pdf
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AT aakratiraina efficacyofbuccalpiroxicaminfiltrationandinferioralveolarnerveblockinpatientswithirreversiblepulpitisaprospectivedoubleblindrandomizedclinicaltrial
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