Occurrence and molecular confirmation of lumpy skin disease among Vechur cattle in Kerala

Lumpy skin disease (LSD) is a notifiable disease caused by LSD virus belonging to the family Poxviridae and Capripoxvirus genus. The disease is characterised by fever, lymphadenopathy and presence of skin nodules. This article reports the occurrence of lumpy skin disease among Vechur cattle and its...

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Main Authors: R. Venkata Manoj, P.V. Tresamol, P. Preena, M. Manoj, R. Anoopraj, K. Justin Davis, V.H. Shyma, K. Vijayakumar
Format: Article
Language:English
Published: Director of Academics and Research, Kerala Veterinary and Animal Sciences University 2025-06-01
Series:Journal of Veterinary and Animal Sciences
Online Access:https://www.jvas.in/article/occurrence-and-molecular-confirmation-of-lumpy-skin-disease-among-vechur-cattle-in-kerala
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author R. Venkata Manoj
P.V. Tresamol
P. Preena
M. Manoj
R. Anoopraj
K. Justin Davis
V.H. Shyma
K. Vijayakumar
author_facet R. Venkata Manoj
P.V. Tresamol
P. Preena
M. Manoj
R. Anoopraj
K. Justin Davis
V.H. Shyma
K. Vijayakumar
author_sort R. Venkata Manoj
collection DOAJ
description Lumpy skin disease (LSD) is a notifiable disease caused by LSD virus belonging to the family Poxviridae and Capripoxvirus genus. The disease is characterised by fever, lymphadenopathy and presence of skin nodules. This article reports the occurrence of lumpy skin disease among Vechur cattle and its molecular confirmation. Two heifers in a Vechur farm were presented with elevated body temperature and nodules of varying sizes on the skin of abdomen and thorax region. Polymerase chain reaction was performed with primers targeting the viral attachment protein, P32 using DNA extracted from skin nodules which yielded amplicons of 192 bp size specific for LSD virus. Haematological and serum biochemical parameters were found to be within in the normal ranges. Histopathology of skin nodules revealed pyogranulomatous myositis and fibrinous vasculitis. Successful treatment was provided with broad spectrum antibiotic, anti-inflammatory drugs and topical antiseptic application. The findings of present study warrant the need for adopting control measures against LSD, including vector control and vaccination in the indigenous breeds of cattle like Vechur.
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issn 0971-0701
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language English
publishDate 2025-06-01
publisher Director of Academics and Research, Kerala Veterinary and Animal Sciences University
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spelling doaj-art-282f9acc9fd64a6a8e7d239cc4d3765b2025-07-11T06:43:28ZengDirector of Academics and Research, Kerala Veterinary and Animal Sciences UniversityJournal of Veterinary and Animal Sciences0971-07012582-06052025-06-0156238739210.51966/jvas.2025.56.2.387-392Occurrence and molecular confirmation of lumpy skin disease among Vechur cattle in KeralaR. Venkata ManojP.V. TresamolP. PreenaM. ManojR. AnooprajK. Justin DavisV.H. ShymaK. VijayakumarLumpy skin disease (LSD) is a notifiable disease caused by LSD virus belonging to the family Poxviridae and Capripoxvirus genus. The disease is characterised by fever, lymphadenopathy and presence of skin nodules. This article reports the occurrence of lumpy skin disease among Vechur cattle and its molecular confirmation. Two heifers in a Vechur farm were presented with elevated body temperature and nodules of varying sizes on the skin of abdomen and thorax region. Polymerase chain reaction was performed with primers targeting the viral attachment protein, P32 using DNA extracted from skin nodules which yielded amplicons of 192 bp size specific for LSD virus. Haematological and serum biochemical parameters were found to be within in the normal ranges. Histopathology of skin nodules revealed pyogranulomatous myositis and fibrinous vasculitis. Successful treatment was provided with broad spectrum antibiotic, anti-inflammatory drugs and topical antiseptic application. The findings of present study warrant the need for adopting control measures against LSD, including vector control and vaccination in the indigenous breeds of cattle like Vechur.https://www.jvas.in/article/occurrence-and-molecular-confirmation-of-lumpy-skin-disease-among-vechur-cattle-in-kerala
spellingShingle R. Venkata Manoj
P.V. Tresamol
P. Preena
M. Manoj
R. Anoopraj
K. Justin Davis
V.H. Shyma
K. Vijayakumar
Occurrence and molecular confirmation of lumpy skin disease among Vechur cattle in Kerala
Journal of Veterinary and Animal Sciences
title Occurrence and molecular confirmation of lumpy skin disease among Vechur cattle in Kerala
title_full Occurrence and molecular confirmation of lumpy skin disease among Vechur cattle in Kerala
title_fullStr Occurrence and molecular confirmation of lumpy skin disease among Vechur cattle in Kerala
title_full_unstemmed Occurrence and molecular confirmation of lumpy skin disease among Vechur cattle in Kerala
title_short Occurrence and molecular confirmation of lumpy skin disease among Vechur cattle in Kerala
title_sort occurrence and molecular confirmation of lumpy skin disease among vechur cattle in kerala
url https://www.jvas.in/article/occurrence-and-molecular-confirmation-of-lumpy-skin-disease-among-vechur-cattle-in-kerala
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