Epigenomics and Schizophrenia: A Literature Review
Aims: Schizophrenia is a severe mental illness, characterized by positive, negative, cognitive, affective symptoms with aggression, marked by disrupted structural and functional brain connectivity, as evidenced by neuroimaging, neurophysiological and neuropathological studies. Recent epigenetic rese...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2025-06-01
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| Series: | BJPsych Open |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2056472425101671/type/journal_article |
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| author | Nishikant Thorat Soham Kulkarni |
| author_facet | Nishikant Thorat Soham Kulkarni |
| author_sort | Nishikant Thorat |
| collection | DOAJ |
| description | Aims: Schizophrenia is a severe mental illness, characterized by positive, negative, cognitive, affective symptoms with aggression, marked by disrupted structural and functional brain connectivity, as evidenced by neuroimaging, neurophysiological and neuropathological studies. Recent epigenetic research highlights the role of deoxyribonucleic acid (DNA) methylation, histone modifications, and non-coding ribonucleic acid (RNA) amongst others in mediating both genetic predisposition and environmental influences on gene expression as seen in schizophrenia. |
| format | Article |
| id | doaj-art-271d39a1f7b14bfea409f6e29cef1803 |
| institution | Matheson Library |
| issn | 2056-4724 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | BJPsych Open |
| spelling | doaj-art-271d39a1f7b14bfea409f6e29cef18032025-07-24T13:40:14ZengCambridge University PressBJPsych Open2056-47242025-06-0111S52S5310.1192/bjo.2025.10167Epigenomics and Schizophrenia: A Literature ReviewNishikant Thorat0Soham Kulkarni1Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, IndiaIndependent Researcher, Pune, IndiaAims: Schizophrenia is a severe mental illness, characterized by positive, negative, cognitive, affective symptoms with aggression, marked by disrupted structural and functional brain connectivity, as evidenced by neuroimaging, neurophysiological and neuropathological studies. Recent epigenetic research highlights the role of deoxyribonucleic acid (DNA) methylation, histone modifications, and non-coding ribonucleic acid (RNA) amongst others in mediating both genetic predisposition and environmental influences on gene expression as seen in schizophrenia.https://www.cambridge.org/core/product/identifier/S2056472425101671/type/journal_article |
| spellingShingle | Nishikant Thorat Soham Kulkarni Epigenomics and Schizophrenia: A Literature Review BJPsych Open |
| title | Epigenomics and Schizophrenia: A Literature Review |
| title_full | Epigenomics and Schizophrenia: A Literature Review |
| title_fullStr | Epigenomics and Schizophrenia: A Literature Review |
| title_full_unstemmed | Epigenomics and Schizophrenia: A Literature Review |
| title_short | Epigenomics and Schizophrenia: A Literature Review |
| title_sort | epigenomics and schizophrenia a literature review |
| url | https://www.cambridge.org/core/product/identifier/S2056472425101671/type/journal_article |
| work_keys_str_mv | AT nishikantthorat epigenomicsandschizophreniaaliteraturereview AT sohamkulkarni epigenomicsandschizophreniaaliteraturereview |