Cryoablation combined with programmed cell death protein 1 (PD-1) inhibitors regulates myeloid-derived suppressor cells (MDSCs) through the JAK2-STAT3-S100A8/A9 axis in mice with Lewis lung carcinoma

Background Cryoablation (Cryo) can enhance the efficacy of tumor immunotherapy, and the synergistic effect of Cryo with immune checkpoint inhibitors has been demonstrated in some tumor models. Because myeloid-derived suppressor cells (MDSCs) accumulate in lung cancer patients and promote tumor progr...

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Bibliographic Details
Main Authors: Jiao Li, Xiaoyu Zhao, Man Qi, Xuxin Chen, Wei Chen, Shuo Zhang, Zhouli Tan, Chunyang Zhang, Zhihai Han
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:International Journal of Hyperthermia
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Online Access:https://www.tandfonline.com/doi/10.1080/02656736.2025.2525444
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