EFFECTIVENESS OF CROSS-PROTECTIVE RECOMBINANT INFLUENZA VACCINE BASED ON CONSERVED EPITOPES OF VIRAL PROTEINS М2 AND HEMAGGLUTININ

EFFECTIVENESS OF CROSS-PROTECTIVE RECOMBINANT INFLUENZA VACCINE BASED ON CONSERVED EPITOPES OF VIRAL PROTEINS М2 AND HEMAGGLUTININ

The influenza virus is the most unique in the level of variability of antigenic and biological properties. Because of constant mutations into genes coding surface viral proteins, in modern vaccines it is necessary to replace 1–2 virus components annually. Traditional influenza vaccines are the strai...

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Bibliographic Details
Main Authors: L. A. Stepanova, M. A. Shuklina, E. A. Blokhina, R. Y. Kotlyarov, A. A. Kovaleva, N. V. Ravin, L. M. Tsybalova
Format: Article
Language:Russian
Published: Journal Infectology 2018-01-01
Series:Журнал инфектологии
Subjects:
influenza virus
recombinant vaccine
m2e ectodomain
ha2
immune response
Online Access:https://journal.niidi.ru/jofin/article/view/655
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