Functional and structural analysis of missense variants in the human PDCD1 Gene

Functional and structural analysis of missense variants in the human PDCD1 Gene

Background: Programmed death-1 (PD-1) is an immune checkpoint receptor that regulates T-cell function by modulating and terminating immune responses. Aim: This study investigates the functional and structural impact of missense single nucleotide polymorphisms in the human Programmed Cell Death 1 (P...

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Bibliographic Details
Main Authors: Hanâ Baba, Meryem Bouqdayr, Anass Abbad, Asmae Saih, Benson R. Kidenya, Mohamed A. Sesay, Simpson Addo, Lahcen Wakrim, Anass Kettani
Format: Article
Language:English
Published: AOSIS 2025-06-01
Series:Journal of Public Health in Africa
Subjects:
programmed death-1 (pd-1)
non-synonymous single nucleotide polymorphisms (nssnps)
in-silico analysis
molecular dynamics (md) simulations
bioinformatics.
Online Access:https://publichealthinafrica.org/index.php/jphia/article/view/1348
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