Combination of LowDose Epigenetic Modifiers and TIC10 for the Activation of Antitumor Immunity and Inhibition of Tumor Growth in Gastrointestinal Cancer

Combination of LowDose Epigenetic Modifiers and TIC10 for the Activation of Antitumor Immunity and Inhibition of Tumor Growth in Gastrointestinal Cancer

ABSTRACT Background Cytotoxic agents remain the mainstay treatment for advanced gastrointestinal cancer. However, the number of cytotoxic agents is limited, and the treatment effect is not satisfactory. Therefore, new agent and combination strategies are to be explored. Methods The antitumor efficac...

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Bibliographic Details
Main Authors: Jianling Zou, Wentao Yang, Shuang Li, Fei Liu, Jinjia Chang, Wenhua Li, Mingzhu Huang, Xiaodong Zhu, Jianyin Zou, Weijian Guo, Zhiyu Chen
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Cancer Medicine
Subjects:
combination therapy
epigenetic modifiers
gastrointestinal cancer
TIC10
tumor microenvironment
Online Access:https://doi.org/10.1002/cam4.71061
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