Differentiation of Lynch syndrome from other forms of non-polyposis colorectal cancer among Russian patients

Differentiation of Lynch syndrome from other forms of non-polyposis colorectal cancer among Russian patients

Aim of investigation. Lynch's syndrome is hereditary syndrome caused by germline mutation in one of reparation genes not coupled bases and causing high risk of colorectal cancer development. At present there are no criteria, allowing to reveal all mutation carriers, and development of new guide...

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Bibliographic Details
Main Authors: A. S. Tsukanov, N. I. Pospehova, V. P. Shubin, I. Yu. Sachkov, S. N. Zhdankina, A. A. Ponomarenko, E. G. Rybakov, S. I. Achkasov, V. N. Kashnikov, S. A. Frolov, Yu. A. Shelygin
Format: Article
Language:Russian
Published: Gastro LLC 2014-08-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Subjects:
lynch's syndrome
colorectal cancer
microsatellite instability
genes mmr
germline mutations
Online Access:https://www.gastro-j.ru/jour/article/view/1106
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