Acneiform Eruptions Caused by Lithium Treatment May Be Related to <i>Demodex</i> Mites (Prostigmata: Demodecidae): A Hypothesis
Acneiform eruptions are a common adverse effect of lithium treatment that may impact adherence. It is not clear why lithium may worsen these lesions and treatment has focused on traditional treatments for acne. <i>Demodex</i> mites are known to commensurably exist in a large fraction of...
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MDPI AG
2025-05-01
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| Series: | Biology |
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| author | Rif S. El-Mallakh Masoud Doroodgar Mehak Pahwa Omar H. A. Elsayed |
| author_facet | Rif S. El-Mallakh Masoud Doroodgar Mehak Pahwa Omar H. A. Elsayed |
| author_sort | Rif S. El-Mallakh |
| collection | DOAJ |
| description | Acneiform eruptions are a common adverse effect of lithium treatment that may impact adherence. It is not clear why lithium may worsen these lesions and treatment has focused on traditional treatments for acne. <i>Demodex</i> mites are known to commensurably exist in a large fraction of humans and are known to cause dermatologic conditions in a minority of individuals. An association with acneiform eruptions is well documented but is generally believed to not be causative. We present a hypothesis that lithium treatment may alter the environment of <i>Demodex</i> mites in a fashion that may increase their propensity to cause disease. If that is accurate, treatment with acaricidal agents may be an additional option. |
| format | Article |
| id | doaj-art-21c9ff9e55e440c6acd39a40c65f8ef1 |
| institution | Matheson Library |
| issn | 2079-7737 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biology |
| spelling | doaj-art-21c9ff9e55e440c6acd39a40c65f8ef12025-06-25T13:30:20ZengMDPI AGBiology2079-77372025-05-0114660510.3390/biology14060605Acneiform Eruptions Caused by Lithium Treatment May Be Related to <i>Demodex</i> Mites (Prostigmata: Demodecidae): A HypothesisRif S. El-Mallakh0Masoud Doroodgar1Mehak Pahwa2Omar H. A. Elsayed3Mood Disorders Research Program, Depression Center, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USAMood Disorders Research Program, Depression Center, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USAMood Disorders Research Program, Depression Center, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USAMood Disorders Research Program, Depression Center, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USAAcneiform eruptions are a common adverse effect of lithium treatment that may impact adherence. It is not clear why lithium may worsen these lesions and treatment has focused on traditional treatments for acne. <i>Demodex</i> mites are known to commensurably exist in a large fraction of humans and are known to cause dermatologic conditions in a minority of individuals. An association with acneiform eruptions is well documented but is generally believed to not be causative. We present a hypothesis that lithium treatment may alter the environment of <i>Demodex</i> mites in a fashion that may increase their propensity to cause disease. If that is accurate, treatment with acaricidal agents may be an additional option.https://www.mdpi.com/2079-7737/14/6/605acneacne vulgaris<i>Demodex</i>lithiumsweat |
| spellingShingle | Rif S. El-Mallakh Masoud Doroodgar Mehak Pahwa Omar H. A. Elsayed Acneiform Eruptions Caused by Lithium Treatment May Be Related to <i>Demodex</i> Mites (Prostigmata: Demodecidae): A Hypothesis Biology acne acne vulgaris <i>Demodex</i> lithium sweat |
| title | Acneiform Eruptions Caused by Lithium Treatment May Be Related to <i>Demodex</i> Mites (Prostigmata: Demodecidae): A Hypothesis |
| title_full | Acneiform Eruptions Caused by Lithium Treatment May Be Related to <i>Demodex</i> Mites (Prostigmata: Demodecidae): A Hypothesis |
| title_fullStr | Acneiform Eruptions Caused by Lithium Treatment May Be Related to <i>Demodex</i> Mites (Prostigmata: Demodecidae): A Hypothesis |
| title_full_unstemmed | Acneiform Eruptions Caused by Lithium Treatment May Be Related to <i>Demodex</i> Mites (Prostigmata: Demodecidae): A Hypothesis |
| title_short | Acneiform Eruptions Caused by Lithium Treatment May Be Related to <i>Demodex</i> Mites (Prostigmata: Demodecidae): A Hypothesis |
| title_sort | acneiform eruptions caused by lithium treatment may be related to i demodex i mites prostigmata demodecidae a hypothesis |
| topic | acne acne vulgaris <i>Demodex</i> lithium sweat |
| url | https://www.mdpi.com/2079-7737/14/6/605 |
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