Computer prediction of acute toxicity of thioderivatives of 3,5-bis(5-mercapto-4-R-4H-1,2,4-triazol-3-yl)phenol

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Computer prediction of acute toxicity of thioderivatives of 3,5-bis(5-mercapto-4-R-4H-1,2,4-triazol-3-yl)phenol

This study presents the computational prediction of acute toxicity for new derivatives of 3,5-bis(5-mercapto-4-R-4H-1,2,4-triazol-3-yl)phenols and their alkylated analogues. The aim of the work was to evaluate the impact of structural changes, particularly alkylation and chain length extension, o...

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Bibliographic Details
Main Authors:	K. K. Isaicheva, A. H. Kaplaushenko
Format:	Article
Language:	English
Published:	Zaporizhzhia State Medical and Pharmaceutical University 2024-11-01
Series:	Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
Subjects:	1 2 4-triazole acute toxicity biological activity
Online Access:	http://pharmed.zsmu.edu.ua/article/view/312443/305696
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