What are the functional outcomes of total laryngeal transplantation? A systematic review of preclinical and clinical studies

What are the functional outcomes of total laryngeal transplantation? A systematic review of preclinical and clinical studies

PurposeThis systematic review aims to evaluate the functional outcomes of total laryngeal transplantation by synthesizing findings from both preclinical and clinical studies. It focuses on assessing postoperative functional recovery, including swallowing, airway patency, phonation, and speech, while...

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Main Authors: Douglas Henderson, Leonard Knoedler, Tobias Niederegger, Jakob Fenske, Olivier Mathieu, Gabriel Hundeshagen, Max Heiland, Curtis L. Cetrulo, D. Gregory Farwell, Jerome R. Lechien, Alexandre G. Lellouch
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
laryngeal transplantation
allotransplantation
vascularized composite allografts
VCA
functional outcomes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1631525/full
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