Surge Dose<sup>®</sup> Formulations of NSAIDs Provide for Ultra-Rapid and Consistent Drug Absorption in Both the Fasted and Fed State as Predicted by Physiologically Based Biopharmaceutics Modelling

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Surge Dose<sup>®</sup> Formulations of NSAIDs Provide for Ultra-Rapid and Consistent Drug Absorption in Both the Fasted and Fed State as Predicted by Physiologically Based Biopharmaceutics Modelling

<b>Background/Objectives:</b> This paper describes the use of physiologically based biopharmaceutics modelling (PBBM) to predict the effect of food on diclofenac and ibuprofen absorption from ultra-rapid-release Surge Dose<sup>®</sup> tablets. <b>Methods:</b> Fast...

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Bibliographic Details
Main Authors:	Harri Dickinson, Zhixin Jiang, Paul A. Dickinson, Ian R. Wilding, Geraldine A. Elliott
Format:	Article
Language:	English
Published:	MDPI AG 2025-05-01
Series:	Pharmaceutics
Subjects:	PBBM (physiologically based biopharmaceutics modelling) diclofenac ibuprofen biorelevant dissolution food effects drug absorption
Online Access:	https://www.mdpi.com/1999-4923/17/6/708
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