EXOME SEQUENCING AND THE DIAGNOSTICS OF COMPLEX DISEASE PREDISPOSITION IN PREVENTIVE MEDICINE
The further development of preventive medicine in the 21st century may be impossible without the assessment of individual patients’ genetic data. At present, genetic methods are the gold standard in the diagnostics of monogenic diseases. Recently, genetic factors linked to complex (multifactorial) d...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2013-12-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/96 |
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| author | N. V. Shcherbakova A. N. Meshkov S. A. Boytsov |
| author_facet | N. V. Shcherbakova A. N. Meshkov S. A. Boytsov |
| author_sort | N. V. Shcherbakova |
| collection | DOAJ |
| description | The further development of preventive medicine in the 21st century may be impossible without the assessment of individual patients’ genetic data. At present, genetic methods are the gold standard in the diagnostics of monogenic diseases. Recently, genetic factors linked to complex (multifactorial) diseases, such as coronary heart disease and arterial hypertension, have been actively explored. This review focuses on the possible identification of new genetic factors of complex disease heritability, using the exome sequencing approach. |
| format | Article |
| id | doaj-art-206efcaca1154bf0b33dba7e5e374a3d |
| institution | Matheson Library |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2013-12-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-206efcaca1154bf0b33dba7e5e374a3d2025-08-04T12:50:19Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252013-12-01126242810.15829/1728-8800-2013-6-24-2896EXOME SEQUENCING AND THE DIAGNOSTICS OF COMPLEX DISEASE PREDISPOSITION IN PREVENTIVE MEDICINEN. V. Shcherbakova0A. N. Meshkov1S. A. Boytsov2State Research Centre for Preventive Medicine, MoscowState Research Centre for Preventive Medicine, MoscowState Research Centre for Preventive Medicine, MoscowThe further development of preventive medicine in the 21st century may be impossible without the assessment of individual patients’ genetic data. At present, genetic methods are the gold standard in the diagnostics of monogenic diseases. Recently, genetic factors linked to complex (multifactorial) diseases, such as coronary heart disease and arterial hypertension, have been actively explored. This review focuses on the possible identification of new genetic factors of complex disease heritability, using the exome sequencing approach.https://cardiovascular.elpub.ru/jour/article/view/96preventive medicinegenetic diagnosticsexome sequencingcomplex or multifactorial diseases |
| spellingShingle | N. V. Shcherbakova A. N. Meshkov S. A. Boytsov EXOME SEQUENCING AND THE DIAGNOSTICS OF COMPLEX DISEASE PREDISPOSITION IN PREVENTIVE MEDICINE Кардиоваскулярная терапия и профилактика preventive medicine genetic diagnostics exome sequencing complex or multifactorial diseases |
| title | EXOME SEQUENCING AND THE DIAGNOSTICS OF COMPLEX DISEASE PREDISPOSITION IN PREVENTIVE MEDICINE |
| title_full | EXOME SEQUENCING AND THE DIAGNOSTICS OF COMPLEX DISEASE PREDISPOSITION IN PREVENTIVE MEDICINE |
| title_fullStr | EXOME SEQUENCING AND THE DIAGNOSTICS OF COMPLEX DISEASE PREDISPOSITION IN PREVENTIVE MEDICINE |
| title_full_unstemmed | EXOME SEQUENCING AND THE DIAGNOSTICS OF COMPLEX DISEASE PREDISPOSITION IN PREVENTIVE MEDICINE |
| title_short | EXOME SEQUENCING AND THE DIAGNOSTICS OF COMPLEX DISEASE PREDISPOSITION IN PREVENTIVE MEDICINE |
| title_sort | exome sequencing and the diagnostics of complex disease predisposition in preventive medicine |
| topic | preventive medicine genetic diagnostics exome sequencing complex or multifactorial diseases |
| url | https://cardiovascular.elpub.ru/jour/article/view/96 |
| work_keys_str_mv | AT nvshcherbakova exomesequencingandthediagnosticsofcomplexdiseasepredispositioninpreventivemedicine AT anmeshkov exomesequencingandthediagnosticsofcomplexdiseasepredispositioninpreventivemedicine AT saboytsov exomesequencingandthediagnosticsofcomplexdiseasepredispositioninpreventivemedicine |