Worldwide practices in pulmonary function test reporting after lung transplantation
Background: Spirometry interpretation after lung transplantation (LTx) is complex, requiring a clear understanding of reference values and normal thresholds globally. Abnormal values are typically based on general population reference standards. Methods: In April 2025, a 10-question online survey wa...
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| Hauptverfasser: | , , , , |
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| Format: | Artikel |
| Sprache: | Englisch |
| Veröffentlicht: |
Elsevier
2025-08-01
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| Schriftenreihe: | JHLT Open |
| Schlagworte: | |
| Online-Zugang: | http://www.sciencedirect.com/science/article/pii/S2950133425001429 |
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| Zusammenfassung: | Background: Spirometry interpretation after lung transplantation (LTx) is complex, requiring a clear understanding of reference values and normal thresholds globally. Abnormal values are typically based on general population reference standards. Methods: In April 2025, a 10-question online survey was conducted among International Society of Heart and Lung Transplantation-members to determine the reference values and normal thresholds used worldwide for post-transplant spirometry interpretation. Results: Responses from 58 centers, covering 22,080 lung transplant recipients and representing ∼40% of global transplant activity, were analyzed. Most patients (63%) were followed in the United States or Canada. Global lung initiative (GLI) reference was used for 60%, with 47% using the race-neutral version. The lower limit of normal (LLN) was reported in only 19% of pulmonary function assessments. Regional differences were noted in obstruction definition and impairment grading. Conclusions: While GLI-reference values are widely adopted, 40% of centers have yet to implement them, and LLN remains underutilized in spirometry reporting after LTx. |
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| ISSN: | 2950-1334 |