Spending, utilization, and price trends for anti-obesity medications in U.S. Medicaid programs: an empirical analysis from 1999 to 2023

BackgroundObesity poses a significant public health and economic challenge in the United States (U.S.), with rising prevalence, particularly among individuals enrolled in Medicaid—the nation’s public health insurance program for low-income populations. Anti-obesity medications (AOMs) have become int...

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Main Authors: Abdulrahman A. Alsuhibani, Marwan A. Alrasheed, Ibrahim S. Alhomoud, Saud Alsahali, Ziyad S. Almalki, Jeff Jianfei Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1537181/full
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author Abdulrahman A. Alsuhibani
Marwan A. Alrasheed
Ibrahim S. Alhomoud
Saud Alsahali
Ziyad S. Almalki
Jeff Jianfei Guo
author_facet Abdulrahman A. Alsuhibani
Marwan A. Alrasheed
Ibrahim S. Alhomoud
Saud Alsahali
Ziyad S. Almalki
Jeff Jianfei Guo
author_sort Abdulrahman A. Alsuhibani
collection DOAJ
description BackgroundObesity poses a significant public health and economic challenge in the United States (U.S.), with rising prevalence, particularly among individuals enrolled in Medicaid—the nation’s public health insurance program for low-income populations. Anti-obesity medications (AOMs) have become integral to managing obesity, but trends in their utilization and spending within Medicaid remain underexplored.ObjectiveTo examine Medicaid’s utilization, reimbursement, and price trends for AOMs from 1999 to 2023.MethodsA retrospective analysis assessing the utilization, reimbursement, and pricing of older and newer AOMs. Yearly prescription numbers and reimbursement were calculated for seven AOMs billed through Medicaid between 1999 and 2023. The average expenditure per prescription was used as an indicator of drug pricing.ResultsAOM prescriptions rose from 13,855 in 1999 to 938,663 in 2023, a 6,674% increase. Spending surged by over 77,805,466% due to the introduction of newer, more effective medications, including Wegovy and tirzepatide. The largest share of the market growth in 2023 was driven by these medications.ConclusionThe significant increase in AOM utilization and spending highlights the growing burden of obesity on Medicaid, emphasizing the need for policy measures to manage rising costs and ensure equitable access to treatment.
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spelling doaj-art-1fc3f2e5f9c74a5eac6fc7715d5ca2a12025-07-16T05:36:54ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-07-011210.3389/fmed.2025.15371811537181Spending, utilization, and price trends for anti-obesity medications in U.S. Medicaid programs: an empirical analysis from 1999 to 2023Abdulrahman A. Alsuhibani0Marwan A. Alrasheed1Ibrahim S. Alhomoud2Saud Alsahali3Ziyad S. Almalki4Jeff Jianfei Guo5Department of Pharmacy Practice, College of Pharmacy, Qassim University, Buraydah, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi ArabiaDepartment of Pharmacy Practice, College of Pharmacy, Qassim University, Buraydah, Saudi ArabiaDepartment of Pharmacy Practice, College of Pharmacy, Qassim University, Buraydah, Saudi ArabiaDepartment of Clinical Pharmacy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi ArabiaJames L. Winkle College of Pharmacy, University of Cincinnati Academic Health Center, Cincinnati, OH, United StatesBackgroundObesity poses a significant public health and economic challenge in the United States (U.S.), with rising prevalence, particularly among individuals enrolled in Medicaid—the nation’s public health insurance program for low-income populations. Anti-obesity medications (AOMs) have become integral to managing obesity, but trends in their utilization and spending within Medicaid remain underexplored.ObjectiveTo examine Medicaid’s utilization, reimbursement, and price trends for AOMs from 1999 to 2023.MethodsA retrospective analysis assessing the utilization, reimbursement, and pricing of older and newer AOMs. Yearly prescription numbers and reimbursement were calculated for seven AOMs billed through Medicaid between 1999 and 2023. The average expenditure per prescription was used as an indicator of drug pricing.ResultsAOM prescriptions rose from 13,855 in 1999 to 938,663 in 2023, a 6,674% increase. Spending surged by over 77,805,466% due to the introduction of newer, more effective medications, including Wegovy and tirzepatide. The largest share of the market growth in 2023 was driven by these medications.ConclusionThe significant increase in AOM utilization and spending highlights the growing burden of obesity on Medicaid, emphasizing the need for policy measures to manage rising costs and ensure equitable access to treatment.https://www.frontiersin.org/articles/10.3389/fmed.2025.1537181/fullobesitypandemicutilizationspendingtrendsMedicaid
spellingShingle Abdulrahman A. Alsuhibani
Marwan A. Alrasheed
Ibrahim S. Alhomoud
Saud Alsahali
Ziyad S. Almalki
Jeff Jianfei Guo
Spending, utilization, and price trends for anti-obesity medications in U.S. Medicaid programs: an empirical analysis from 1999 to 2023
Frontiers in Medicine
obesity
pandemic
utilization
spending
trends
Medicaid
title Spending, utilization, and price trends for anti-obesity medications in U.S. Medicaid programs: an empirical analysis from 1999 to 2023
title_full Spending, utilization, and price trends for anti-obesity medications in U.S. Medicaid programs: an empirical analysis from 1999 to 2023
title_fullStr Spending, utilization, and price trends for anti-obesity medications in U.S. Medicaid programs: an empirical analysis from 1999 to 2023
title_full_unstemmed Spending, utilization, and price trends for anti-obesity medications in U.S. Medicaid programs: an empirical analysis from 1999 to 2023
title_short Spending, utilization, and price trends for anti-obesity medications in U.S. Medicaid programs: an empirical analysis from 1999 to 2023
title_sort spending utilization and price trends for anti obesity medications in u s medicaid programs an empirical analysis from 1999 to 2023
topic obesity
pandemic
utilization
spending
trends
Medicaid
url https://www.frontiersin.org/articles/10.3389/fmed.2025.1537181/full
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