HyenaCircle: a HyenaDNA-based pretrained large language model for long eccDNA prediction
IntroductionExtrachromosomal circular DNA (eccDNA) represents a class of circular DNA molecules derived from chromosomes with diverse roles in disease. Long eccDNAs (typically 1–5 kb) pose detection challenges due to their large size, hindering functional studies. We propose HyenaCircle, a novel dee...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-06-01
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| Series: | Frontiers in Genetics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2025.1641162/full |
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