LOFGREN’S SYNDROME: CLINICAL CASE

Sarcoidosis is an inflammatory disease characterized by the formation of non-caseating granulomas in various organs and tissues. The clinical signs of sarcoidosis are determined by the number of affected organs, the degree of their structural and functional impairment, and the severity of inflammato...

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Main Authors: A. E. Shklyaev, E. A. Semenovykh, L. V. Ivanova, A. N. Vedekhina
Format: Article
Language:Russian
Published: SINAPS LLC 2019-07-01
Series:Архивъ внутренней медицины
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Online Access:https://www.medarhive.ru/jour/article/view/952
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author A. E. Shklyaev
E. A. Semenovykh
L. V. Ivanova
A. N. Vedekhina
author_facet A. E. Shklyaev
E. A. Semenovykh
L. V. Ivanova
A. N. Vedekhina
author_sort A. E. Shklyaev
collection DOAJ
description Sarcoidosis is an inflammatory disease characterized by the formation of non-caseating granulomas in various organs and tissues. The clinical signs of sarcoidosis are determined by the number of affected organs, the degree of their structural and functional impairment, and the severity of inflammatory symptoms. The article presents a clinical observation of one of the forms of sarcoidosis — Lofgren’s syndrome, which is characterized by a triad of intrathoracic lymphadenopathy, acute arthritis and erythema nodosum. The diagnosis was confirmed histologically. Under the prescribed treatment, signs of acute inflammation reversed and the patient’s state improved. The authors emphasize that they do not recommend widespread use of systemic glucocorticosteroids in patients with this disease, since their use may be associated with a relapsing course.
format Article
id doaj-art-1f8712b8f4254b61ba3a6de01e58e94f
institution Matheson Library
issn 2226-6704
2411-6564
language Russian
publishDate 2019-07-01
publisher SINAPS LLC
record_format Article
series Архивъ внутренней медицины
spelling doaj-art-1f8712b8f4254b61ba3a6de01e58e94f2025-08-04T14:09:47ZrusSINAPS LLCАрхивъ внутренней медицины2226-67042411-65642019-07-019430831210.20514/2226-6704-2019-9-4-308-312750LOFGREN’S SYNDROME: CLINICAL CASEA. E. Shklyaev0E. A. Semenovykh1L. V. Ivanova2A. N. Vedekhina3Izhevsk state medical AcademyIzhevsk state medical AcademyRepublican Clinical Diagnostic Center, Department of RheumatologyRepublican Clinical Diagnostic Center, Department of RheumatologySarcoidosis is an inflammatory disease characterized by the formation of non-caseating granulomas in various organs and tissues. The clinical signs of sarcoidosis are determined by the number of affected organs, the degree of their structural and functional impairment, and the severity of inflammatory symptoms. The article presents a clinical observation of one of the forms of sarcoidosis — Lofgren’s syndrome, which is characterized by a triad of intrathoracic lymphadenopathy, acute arthritis and erythema nodosum. The diagnosis was confirmed histologically. Under the prescribed treatment, signs of acute inflammation reversed and the patient’s state improved. The authors emphasize that they do not recommend widespread use of systemic glucocorticosteroids in patients with this disease, since their use may be associated with a relapsing course.https://www.medarhive.ru/jour/article/view/952lofgren’s syndromesarcoidosisacute arthritis
spellingShingle A. E. Shklyaev
E. A. Semenovykh
L. V. Ivanova
A. N. Vedekhina
LOFGREN’S SYNDROME: CLINICAL CASE
Архивъ внутренней медицины
lofgren’s syndrome
sarcoidosis
acute arthritis
title LOFGREN’S SYNDROME: CLINICAL CASE
title_full LOFGREN’S SYNDROME: CLINICAL CASE
title_fullStr LOFGREN’S SYNDROME: CLINICAL CASE
title_full_unstemmed LOFGREN’S SYNDROME: CLINICAL CASE
title_short LOFGREN’S SYNDROME: CLINICAL CASE
title_sort lofgren s syndrome clinical case
topic lofgren’s syndrome
sarcoidosis
acute arthritis
url https://www.medarhive.ru/jour/article/view/952
work_keys_str_mv AT aeshklyaev lofgrenssyndromeclinicalcase
AT easemenovykh lofgrenssyndromeclinicalcase
AT lvivanova lofgrenssyndromeclinicalcase
AT anvedekhina lofgrenssyndromeclinicalcase