LOFGREN’S SYNDROME: CLINICAL CASE
Sarcoidosis is an inflammatory disease characterized by the formation of non-caseating granulomas in various organs and tissues. The clinical signs of sarcoidosis are determined by the number of affected organs, the degree of their structural and functional impairment, and the severity of inflammato...
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SINAPS LLC
2019-07-01
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Series: | Архивъ внутренней медицины |
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Online Access: | https://www.medarhive.ru/jour/article/view/952 |
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author | A. E. Shklyaev E. A. Semenovykh L. V. Ivanova A. N. Vedekhina |
author_facet | A. E. Shklyaev E. A. Semenovykh L. V. Ivanova A. N. Vedekhina |
author_sort | A. E. Shklyaev |
collection | DOAJ |
description | Sarcoidosis is an inflammatory disease characterized by the formation of non-caseating granulomas in various organs and tissues. The clinical signs of sarcoidosis are determined by the number of affected organs, the degree of their structural and functional impairment, and the severity of inflammatory symptoms. The article presents a clinical observation of one of the forms of sarcoidosis — Lofgren’s syndrome, which is characterized by a triad of intrathoracic lymphadenopathy, acute arthritis and erythema nodosum. The diagnosis was confirmed histologically. Under the prescribed treatment, signs of acute inflammation reversed and the patient’s state improved. The authors emphasize that they do not recommend widespread use of systemic glucocorticosteroids in patients with this disease, since their use may be associated with a relapsing course. |
format | Article |
id | doaj-art-1f8712b8f4254b61ba3a6de01e58e94f |
institution | Matheson Library |
issn | 2226-6704 2411-6564 |
language | Russian |
publishDate | 2019-07-01 |
publisher | SINAPS LLC |
record_format | Article |
series | Архивъ внутренней медицины |
spelling | doaj-art-1f8712b8f4254b61ba3a6de01e58e94f2025-08-04T14:09:47ZrusSINAPS LLCАрхивъ внутренней медицины2226-67042411-65642019-07-019430831210.20514/2226-6704-2019-9-4-308-312750LOFGREN’S SYNDROME: CLINICAL CASEA. E. Shklyaev0E. A. Semenovykh1L. V. Ivanova2A. N. Vedekhina3Izhevsk state medical AcademyIzhevsk state medical AcademyRepublican Clinical Diagnostic Center, Department of RheumatologyRepublican Clinical Diagnostic Center, Department of RheumatologySarcoidosis is an inflammatory disease characterized by the formation of non-caseating granulomas in various organs and tissues. The clinical signs of sarcoidosis are determined by the number of affected organs, the degree of their structural and functional impairment, and the severity of inflammatory symptoms. The article presents a clinical observation of one of the forms of sarcoidosis — Lofgren’s syndrome, which is characterized by a triad of intrathoracic lymphadenopathy, acute arthritis and erythema nodosum. The diagnosis was confirmed histologically. Under the prescribed treatment, signs of acute inflammation reversed and the patient’s state improved. The authors emphasize that they do not recommend widespread use of systemic glucocorticosteroids in patients with this disease, since their use may be associated with a relapsing course.https://www.medarhive.ru/jour/article/view/952lofgren’s syndromesarcoidosisacute arthritis |
spellingShingle | A. E. Shklyaev E. A. Semenovykh L. V. Ivanova A. N. Vedekhina LOFGREN’S SYNDROME: CLINICAL CASE Архивъ внутренней медицины lofgren’s syndrome sarcoidosis acute arthritis |
title | LOFGREN’S SYNDROME: CLINICAL CASE |
title_full | LOFGREN’S SYNDROME: CLINICAL CASE |
title_fullStr | LOFGREN’S SYNDROME: CLINICAL CASE |
title_full_unstemmed | LOFGREN’S SYNDROME: CLINICAL CASE |
title_short | LOFGREN’S SYNDROME: CLINICAL CASE |
title_sort | lofgren s syndrome clinical case |
topic | lofgren’s syndrome sarcoidosis acute arthritis |
url | https://www.medarhive.ru/jour/article/view/952 |
work_keys_str_mv | AT aeshklyaev lofgrenssyndromeclinicalcase AT easemenovykh lofgrenssyndromeclinicalcase AT lvivanova lofgrenssyndromeclinicalcase AT anvedekhina lofgrenssyndromeclinicalcase |