Liquid Chromatography-Mass Spectrometry for the Geographical Sourcing of Cannabis sativa L.
Marijuana, dried and ground Cannabis, is the most consumed illicit drug in the world, despite many undesirable and risky effects to human health that are caused by its use. The medicinal use and/or legal recreational use of Cannabis has also been rising worldwide. Therefore, traceability methodolog...
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| Format: | Article |
| Language: | English |
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Instituto Paulista de Estudos Bioéticos e Jurídicos
2025-06-01
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| Series: | Brazilian Journal of Forensic Sciences, Medical Law and Bioethics |
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| Online Access: | https://www.bjfs.org/bjfs/bjfs/article/view/980 |
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| author | Mariana Fernandes Ramos Fernanda Rodrigues Salazar Sabrina Laíz Büttenbender João A. Coblinski Mauro Sander Fett Renata Pereira Limberger Flávio A. Oliveira Camargo |
| author_facet | Mariana Fernandes Ramos Fernanda Rodrigues Salazar Sabrina Laíz Büttenbender João A. Coblinski Mauro Sander Fett Renata Pereira Limberger Flávio A. Oliveira Camargo |
| author_sort | Mariana Fernandes Ramos |
| collection | DOAJ |
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Marijuana, dried and ground Cannabis, is the most consumed illicit drug in the world, despite many undesirable and risky effects to human health that are caused by its use. The medicinal use and/or legal recreational use of Cannabis has also been rising worldwide. Therefore, traceability methodologies are increasingly gaining importance whether for forensic use, such as drug trafficking eradication, or for quality control purposes of legal medicinal Cannabis. The goal of this study was to analyze Cannabis samples seized by the Brazilian Federal Police in eradication operations occurred in 2014 and 2017, by means of liquid chromatography-mass spectrometry (LC-MS) and linear discriminant analysis (LDA), aiming to trace their geographical origin. The LDA showed 39.13% accuracy in sourcing the samples from 2014, and 80.95% for the 2017 samples, which indicates that high temperature in the drying step and plant age negatively affect data accuracy.
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| format | Article |
| id | doaj-art-1f6ea2f291274b19b571d13e0dbf636e |
| institution | Matheson Library |
| issn | 2237-261X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Instituto Paulista de Estudos Bioéticos e Jurídicos |
| record_format | Article |
| series | Brazilian Journal of Forensic Sciences, Medical Law and Bioethics |
| spelling | doaj-art-1f6ea2f291274b19b571d13e0dbf636e2025-06-29T21:58:07ZengInstituto Paulista de Estudos Bioéticos e JurídicosBrazilian Journal of Forensic Sciences, Medical Law and Bioethics2237-261X2025-06-0113110.17063/bjfs13(1)y202542-59Liquid Chromatography-Mass Spectrometry for the Geographical Sourcing of Cannabis sativa L.Mariana Fernandes Ramos0Fernanda Rodrigues Salazar1Sabrina Laíz Büttenbender2João A. Coblinski3Mauro Sander Fett4Renata Pereira Limberger5Flávio A. Oliveira Camargo6Federal University of Rio Grande do Sul, Porto Alegre, RS, BrazilFederal University of Rio Grande do Sul, Porto Alegre, RS, BrazilSciences Graduate Program, Federal University of Rio Grande do Sul, Porto Alegre, RS, BrazilFederal University of Rio Grande do Sul, Porto Alegre, RS, BrazilBrazilian Federal Police, Porto Alegre, RS, BrazilFederal University of Rio Grande do Sul, Porto Alegre, RS, BrazilFederal University of Rio Grande do Sul, Porto Alegre, RS, Brazil Marijuana, dried and ground Cannabis, is the most consumed illicit drug in the world, despite many undesirable and risky effects to human health that are caused by its use. The medicinal use and/or legal recreational use of Cannabis has also been rising worldwide. Therefore, traceability methodologies are increasingly gaining importance whether for forensic use, such as drug trafficking eradication, or for quality control purposes of legal medicinal Cannabis. The goal of this study was to analyze Cannabis samples seized by the Brazilian Federal Police in eradication operations occurred in 2014 and 2017, by means of liquid chromatography-mass spectrometry (LC-MS) and linear discriminant analysis (LDA), aiming to trace their geographical origin. The LDA showed 39.13% accuracy in sourcing the samples from 2014, and 80.95% for the 2017 samples, which indicates that high temperature in the drying step and plant age negatively affect data accuracy. https://www.bjfs.org/bjfs/bjfs/article/view/980LC-MSHempMarijuanaTHCCBNLDA |
| spellingShingle | Mariana Fernandes Ramos Fernanda Rodrigues Salazar Sabrina Laíz Büttenbender João A. Coblinski Mauro Sander Fett Renata Pereira Limberger Flávio A. Oliveira Camargo Liquid Chromatography-Mass Spectrometry for the Geographical Sourcing of Cannabis sativa L. Brazilian Journal of Forensic Sciences, Medical Law and Bioethics LC-MS Hemp Marijuana THC CBN LDA |
| title | Liquid Chromatography-Mass Spectrometry for the Geographical Sourcing of Cannabis sativa L. |
| title_full | Liquid Chromatography-Mass Spectrometry for the Geographical Sourcing of Cannabis sativa L. |
| title_fullStr | Liquid Chromatography-Mass Spectrometry for the Geographical Sourcing of Cannabis sativa L. |
| title_full_unstemmed | Liquid Chromatography-Mass Spectrometry for the Geographical Sourcing of Cannabis sativa L. |
| title_short | Liquid Chromatography-Mass Spectrometry for the Geographical Sourcing of Cannabis sativa L. |
| title_sort | liquid chromatography mass spectrometry for the geographical sourcing of cannabis sativa l |
| topic | LC-MS Hemp Marijuana THC CBN LDA |
| url | https://www.bjfs.org/bjfs/bjfs/article/view/980 |
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