Stability of 3', 5'-o-(tetraisopropyldisiloxane-1,3-diyl)nucleosides in the presence of lewis acids
Trimethylsilyl trifluoromethanesulfonate catalyzes effective isomerization of 3',5'-O-(tetraisopropyldisiloxane1,3-diyl,TIPDS)nucleosides in 1,2-dicloroethane at 0C into 2',3'-O-TIPDS-derivatives to give 55-90% yields. On the other hand 3',5'-O-TIPDS-nucleosides except...
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| Format: | Article |
| Language: | Russian |
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MIREA - Russian Technological University
2008-10-01
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| Series: | Тонкие химические технологии |
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| Online Access: | https://www.finechem-mirea.ru/jour/article/view/1538 |
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| _version_ | 1839581436773924864 |
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| author | I. V. Kulikova D. A. Muradova S. N. Mikhailov |
| author_facet | I. V. Kulikova D. A. Muradova S. N. Mikhailov |
| author_sort | I. V. Kulikova |
| collection | DOAJ |
| description | Trimethylsilyl trifluoromethanesulfonate catalyzes effective isomerization of 3',5'-O-(tetraisopropyldisiloxane1,3-diyl,TIPDS)nucleosides in 1,2-dicloroethane at 0C into 2',3'-O-TIPDS-derivatives to give 55-90% yields. On the other hand 3',5'-O-TIPDS-nucleosides except for uridine derivative 1a were found to be stable in the in the presence of tin tetrachloride and boron trifluoride etherate |
| format | Article |
| id | doaj-art-1f5d1ba4edfa47a28e9abd19f14ce2eb |
| institution | Matheson Library |
| issn | 2410-6593 2686-7575 |
| language | Russian |
| publishDate | 2008-10-01 |
| publisher | MIREA - Russian Technological University |
| record_format | Article |
| series | Тонкие химические технологии |
| spelling | doaj-art-1f5d1ba4edfa47a28e9abd19f14ce2eb2025-08-04T10:19:31ZrusMIREA - Russian Technological UniversityТонкие химические технологии2410-65932686-75752008-10-013593981533Stability of 3', 5'-o-(tetraisopropyldisiloxane-1,3-diyl)nucleosides in the presence of lewis acidsI. V. Kulikova0D. A. Muradova1S. N. Mikhailov2Институт молекулярной биологии РАН им. В.А. ЭнгельгардтаИнститут молекулярной биологии РАН им. В.А. ЭнгельгардтаИнститут молекулярной биологии РАН им. В.А. ЭнгельгардтаTrimethylsilyl trifluoromethanesulfonate catalyzes effective isomerization of 3',5'-O-(tetraisopropyldisiloxane1,3-diyl,TIPDS)nucleosides in 1,2-dicloroethane at 0C into 2',3'-O-TIPDS-derivatives to give 55-90% yields. On the other hand 3',5'-O-TIPDS-nucleosides except for uridine derivative 1a were found to be stable in the in the presence of tin tetrachloride and boron trifluoride etheratehttps://www.finechem-mirea.ru/jour/article/view/1538защитные группы нуклеозидов, изомеризация, 3′,5′-o-(тетраизопропилдисилоксан-1,3-диил)нуклеозиды, триметилсилилтрифторметан-сульфонат. |
| spellingShingle | I. V. Kulikova D. A. Muradova S. N. Mikhailov Stability of 3', 5'-o-(tetraisopropyldisiloxane-1,3-diyl)nucleosides in the presence of lewis acids Тонкие химические технологии защитные группы нуклеозидов, изомеризация, 3′,5′-o-(тетраизопропилдисилоксан-1,3-диил)нуклеозиды, триметилсилилтрифторметан-сульфонат. |
| title | Stability of 3', 5'-o-(tetraisopropyldisiloxane-1,3-diyl)nucleosides in the presence of lewis acids |
| title_full | Stability of 3', 5'-o-(tetraisopropyldisiloxane-1,3-diyl)nucleosides in the presence of lewis acids |
| title_fullStr | Stability of 3', 5'-o-(tetraisopropyldisiloxane-1,3-diyl)nucleosides in the presence of lewis acids |
| title_full_unstemmed | Stability of 3', 5'-o-(tetraisopropyldisiloxane-1,3-diyl)nucleosides in the presence of lewis acids |
| title_short | Stability of 3', 5'-o-(tetraisopropyldisiloxane-1,3-diyl)nucleosides in the presence of lewis acids |
| title_sort | stability of 3 5 o tetraisopropyldisiloxane 1 3 diyl nucleosides in the presence of lewis acids |
| topic | защитные группы нуклеозидов, изомеризация, 3′,5′-o-(тетраизопропилдисилоксан-1,3-диил)нуклеозиды, триметилсилилтрифторметан-сульфонат. |
| url | https://www.finechem-mirea.ru/jour/article/view/1538 |
| work_keys_str_mv | AT ivkulikova stabilityof35otetraisopropyldisiloxane13diylnucleosidesinthepresenceoflewisacids AT damuradova stabilityof35otetraisopropyldisiloxane13diylnucleosidesinthepresenceoflewisacids AT snmikhailov stabilityof35otetraisopropyldisiloxane13diylnucleosidesinthepresenceoflewisacids |