Genetic silencing of KCa3.1 inhibits atherosclerosis in ApoE null mice
Increased expression of KCa3.1 has been found in vascular smooth muscle cells (SMC), macrophages, and T cells in atherosclerotic lesions from humans and mice. Pharmacological inhibition of KCa3.1 in limiting atherosclerosis has been demonstrated in mice and pigs, however direct, loss-of-function, i....
Saved in:
Main Authors: | P. Alam, D. L. Tharp, H. J. Bowles, L. A. Grisanti, H. Bui, S. B. Bender, D. K. Bowles |
---|---|
Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2025-12-01
|
Series: | Channels |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/19336950.2025.2538864 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The simultaneous use of CRISPR/Cas9 to knock out the PI3Kca gene with radiation to enhance radiosensitivity and inhibit tumor growth in breast cancer
by: Amir Danyaei, et al.
Published: (2024-12-01) -
Exploration of the Possible Relationships Between Gut and Hypothalamic Inflammation and Allopregnanolone: Preclinical Findings in a Post-Finasteride Rat Model
by: Silvia Diviccaro, et al.
Published: (2025-07-01) -
Virus-induced gene silencing
by: XU You-ping, et al.
Published: (2008-03-01) -
Interleukin-31: A Pro-inflammatory Oriented Cytokine
by: Giuseppe Murdaca, et al.
Published: (2025-06-01) -
Cvill6 and Cvill7: Potent and Selective Peptide Blockers of Kv1.2 Ion Channel Isolated from Mexican Scorpion <i>Centruroides villegasi</i>
by: Kashmala Shakeel, et al.
Published: (2025-06-01)