Prevalence and predictive factors for vitamin D deficiency in pregnant Lebanese women: a retrospective cohort study
Objective This study aimed to determine the prevalence of vitamin D deficiency and its associated factors among women attending women’s health clinics at a university medical center in Lebanon.Methods We retrospectively reviewed clinical and obstetric data, including 25-hydroxyvitamin D [25OHD] seru...
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Taylor & Francis Group
2025-12-01
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| Series: | Gynecological Endocrinology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/09513590.2025.2521531 |
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| author | Muhieddine Seoud Iman Jaafar Dalal Kojok Sara Sleiman Talal Seoud Ghina Ghaziri Fadi Mirza |
| author_facet | Muhieddine Seoud Iman Jaafar Dalal Kojok Sara Sleiman Talal Seoud Ghina Ghaziri Fadi Mirza |
| author_sort | Muhieddine Seoud |
| collection | DOAJ |
| description | Objective This study aimed to determine the prevalence of vitamin D deficiency and its associated factors among women attending women’s health clinics at a university medical center in Lebanon.Methods We retrospectively reviewed clinical and obstetric data, including 25-hydroxyvitamin D [25OHD] serum levels and vitamin D3 supplementation, from 873 healthy singleton pregnancies delivered between 2006 and 2017. Women with preexisting comorbidities or prior gestational complications were excluded. VDD was defined as a 25OHD serum level <20 ng/ml.Results At baseline, 63% of participants were vitamin D deficient. Poisson regression was used to identify independent predictors of deficiency. In early gestation, 25OHD levels varied significantly by age, pre-pregnancy BMI, parity, smoking status, and season of presentation (all p < 0.05). At late gestation, vitamin D levels were associated with pre-pregnancy BMI, hemoglobin status at delivery, and vitamin D status at early gestation. Women with 25OHD <20 ng/ml at late gestation were more likely to be anemic compared to those with levels ≥20 ng/ml (adjusted odds ratio 1.6; 95% CI: 1.1–2.5).Conclusion Vitamin D deficiency is highly prevalent among pregnant Lebanese women. Identified risk factors including higher BMI, younger age, multiparity, and anemia should prompt consideration of more aggressive vitamin D supplementation strategies for women planning pregnancy.Synopsis Vitamin D deficiency is quite prevalent among pregnant women in the Middle East. We aim to report the prevalence of Vitamin D deficiency and its associated predictors during pregnancy. |
| format | Article |
| id | doaj-art-1ede97c5a9554837bc7f3e7c9b10b74c |
| institution | Matheson Library |
| issn | 0951-3590 1473-0766 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Gynecological Endocrinology |
| spelling | doaj-art-1ede97c5a9554837bc7f3e7c9b10b74c2025-06-24T17:27:55ZengTaylor & Francis GroupGynecological Endocrinology0951-35901473-07662025-12-0141110.1080/09513590.2025.2521531Prevalence and predictive factors for vitamin D deficiency in pregnant Lebanese women: a retrospective cohort studyMuhieddine Seoud0Iman Jaafar1Dalal Kojok2Sara Sleiman3Talal Seoud4Ghina Ghaziri5Fadi Mirza6Department of Obstetrics and Gynecology, American University of Beirut, Beirut, LebanonDepartment of Obstetrics and Gynecology, American University of Beirut, Beirut, LebanonDepartment of Obstetrics and Gynecology, American University of Beirut, Beirut, LebanonFaculty of Medicine, American University of Beirut, Beirut, LebanonFaculty of Medicine, American University of Beirut, Beirut, LebanonDepartment of Obstetrics and Gynecology, American University of Beirut, Beirut, LebanonDepartment of Obstetrics and Gynecology, American University of Beirut, Beirut, LebanonObjective This study aimed to determine the prevalence of vitamin D deficiency and its associated factors among women attending women’s health clinics at a university medical center in Lebanon.Methods We retrospectively reviewed clinical and obstetric data, including 25-hydroxyvitamin D [25OHD] serum levels and vitamin D3 supplementation, from 873 healthy singleton pregnancies delivered between 2006 and 2017. Women with preexisting comorbidities or prior gestational complications were excluded. VDD was defined as a 25OHD serum level <20 ng/ml.Results At baseline, 63% of participants were vitamin D deficient. Poisson regression was used to identify independent predictors of deficiency. In early gestation, 25OHD levels varied significantly by age, pre-pregnancy BMI, parity, smoking status, and season of presentation (all p < 0.05). At late gestation, vitamin D levels were associated with pre-pregnancy BMI, hemoglobin status at delivery, and vitamin D status at early gestation. Women with 25OHD <20 ng/ml at late gestation were more likely to be anemic compared to those with levels ≥20 ng/ml (adjusted odds ratio 1.6; 95% CI: 1.1–2.5).Conclusion Vitamin D deficiency is highly prevalent among pregnant Lebanese women. Identified risk factors including higher BMI, younger age, multiparity, and anemia should prompt consideration of more aggressive vitamin D supplementation strategies for women planning pregnancy.Synopsis Vitamin D deficiency is quite prevalent among pregnant women in the Middle East. We aim to report the prevalence of Vitamin D deficiency and its associated predictors during pregnancy.https://www.tandfonline.com/doi/10.1080/09513590.2025.2521531Pregnant womenVitamin DVitamin D deficiency |
| spellingShingle | Muhieddine Seoud Iman Jaafar Dalal Kojok Sara Sleiman Talal Seoud Ghina Ghaziri Fadi Mirza Prevalence and predictive factors for vitamin D deficiency in pregnant Lebanese women: a retrospective cohort study Gynecological Endocrinology Pregnant women Vitamin D Vitamin D deficiency |
| title | Prevalence and predictive factors for vitamin D deficiency in pregnant Lebanese women: a retrospective cohort study |
| title_full | Prevalence and predictive factors for vitamin D deficiency in pregnant Lebanese women: a retrospective cohort study |
| title_fullStr | Prevalence and predictive factors for vitamin D deficiency in pregnant Lebanese women: a retrospective cohort study |
| title_full_unstemmed | Prevalence and predictive factors for vitamin D deficiency in pregnant Lebanese women: a retrospective cohort study |
| title_short | Prevalence and predictive factors for vitamin D deficiency in pregnant Lebanese women: a retrospective cohort study |
| title_sort | prevalence and predictive factors for vitamin d deficiency in pregnant lebanese women a retrospective cohort study |
| topic | Pregnant women Vitamin D Vitamin D deficiency |
| url | https://www.tandfonline.com/doi/10.1080/09513590.2025.2521531 |
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