Hederagenin's uric acid-lowering effects in hyperuricemic mice: Mechanistic insights from molecular docking and in vivo analysis.

This study explored the uric acid-lowering effects of hederagenin (HD) through molecular docking analysis and a chronic hyperuricemia (HUA) mouse model. Molecular docking was performed to evaluate HD's interactions key urate-regulating proteins, including xanthine oxidase (XOD), ABCG2, OAT1, UR...

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Bibliographic Details
Main Authors: Ping Chen, Ya-Ni Tian, Jing-Tao Wang, Xiang-Lin Yin, Bao-Sheng Guan, Xue Bai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0326317
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