Determination of Advanced Oxidation Protein Products, E3 SUMO-Protein Ligase NSE2[NSMCE2], as a Marker to Predict Child Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia (ALL) is a cancer of the blood and bone marrow (spongy tissue in the center of bone). In ALL, too many bone marrow stem cells develop into a type of white blood cell called lymphocytes. These abnormal lymphocytes are not able to fight infection very well. The aim of this...
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University of Baghdad, College of Science for Women
2014-03-01
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Series: | مجلة بغداد للعلوم |
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Online Access: | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1543 |
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author | Baghdad Science Journal |
author_facet | Baghdad Science Journal |
author_sort | Baghdad Science Journal |
collection | DOAJ |
description | Acute lymphoblastic leukemia (ALL) is a cancer of the blood and bone marrow (spongy tissue in the center of bone). In ALL, too many bone marrow stem cells develop into a type of white blood cell called lymphocytes. These abnormal lymphocytes are not able to fight infection very well. The aim of this study was to investigate possible links between E3 SUMO-Protein Ligase NSE2 [NSMCE2] and increase DNA damage in the childhood patients with Acute lymphoblastic leukemia (ALL). Laboratory investigations including hemoglobin(Hb) ,white blood cell (WBC) , serum total protein , albumin ,globulin , in addition to serum total antioxidant activity (TAA) , Advanced oxidation protein products(AOPP) and E3 SUMO-Protein Ligase NSE2[NSMCE2]. Blood samples were collected from 60 patients diagnosed to Acute lymphoblastic leukemia (ALL) after one month treatment with induction therapy. Age and sex matched 30 healthy persons selected as control.serum total protein , albumin and globulin showed A significant decrease in patients group when compared to control group( P |
format | Article |
id | doaj-art-1e546b4cd6c3439f81a1a87827df97e2 |
institution | Matheson Library |
issn | 2078-8665 2411-7986 |
language | English |
publishDate | 2014-03-01 |
publisher | University of Baghdad, College of Science for Women |
record_format | Article |
series | مجلة بغداد للعلوم |
spelling | doaj-art-1e546b4cd6c3439f81a1a87827df97e22025-08-02T02:54:28ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862014-03-0111110.21123/bsj.11.1.128-138Determination of Advanced Oxidation Protein Products, E3 SUMO-Protein Ligase NSE2[NSMCE2], as a Marker to Predict Child Acute Lymphoblastic LeukemiaBaghdad Science JournalAcute lymphoblastic leukemia (ALL) is a cancer of the blood and bone marrow (spongy tissue in the center of bone). In ALL, too many bone marrow stem cells develop into a type of white blood cell called lymphocytes. These abnormal lymphocytes are not able to fight infection very well. The aim of this study was to investigate possible links between E3 SUMO-Protein Ligase NSE2 [NSMCE2] and increase DNA damage in the childhood patients with Acute lymphoblastic leukemia (ALL). Laboratory investigations including hemoglobin(Hb) ,white blood cell (WBC) , serum total protein , albumin ,globulin , in addition to serum total antioxidant activity (TAA) , Advanced oxidation protein products(AOPP) and E3 SUMO-Protein Ligase NSE2[NSMCE2]. Blood samples were collected from 60 patients diagnosed to Acute lymphoblastic leukemia (ALL) after one month treatment with induction therapy. Age and sex matched 30 healthy persons selected as control.serum total protein , albumin and globulin showed A significant decrease in patients group when compared to control group( Phttp://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1543Acute lymphoblastic leukemia (ALL) , NSMCE2,AOPP, total antioxidant activity |
spellingShingle | Baghdad Science Journal Determination of Advanced Oxidation Protein Products, E3 SUMO-Protein Ligase NSE2[NSMCE2], as a Marker to Predict Child Acute Lymphoblastic Leukemia مجلة بغداد للعلوم Acute lymphoblastic leukemia (ALL) , NSMCE2,AOPP, total antioxidant activity |
title | Determination of Advanced Oxidation Protein Products, E3 SUMO-Protein Ligase NSE2[NSMCE2], as a Marker to Predict Child Acute Lymphoblastic Leukemia |
title_full | Determination of Advanced Oxidation Protein Products, E3 SUMO-Protein Ligase NSE2[NSMCE2], as a Marker to Predict Child Acute Lymphoblastic Leukemia |
title_fullStr | Determination of Advanced Oxidation Protein Products, E3 SUMO-Protein Ligase NSE2[NSMCE2], as a Marker to Predict Child Acute Lymphoblastic Leukemia |
title_full_unstemmed | Determination of Advanced Oxidation Protein Products, E3 SUMO-Protein Ligase NSE2[NSMCE2], as a Marker to Predict Child Acute Lymphoblastic Leukemia |
title_short | Determination of Advanced Oxidation Protein Products, E3 SUMO-Protein Ligase NSE2[NSMCE2], as a Marker to Predict Child Acute Lymphoblastic Leukemia |
title_sort | determination of advanced oxidation protein products e3 sumo protein ligase nse2 nsmce2 as a marker to predict child acute lymphoblastic leukemia |
topic | Acute lymphoblastic leukemia (ALL) , NSMCE2,AOPP, total antioxidant activity |
url | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1543 |
work_keys_str_mv | AT baghdadsciencejournal determinationofadvancedoxidationproteinproductse3sumoproteinligasense2nsmce2asamarkertopredictchildacutelymphoblasticleukemia |