Wound healing in glaucoma surgery. Part 1. Wound healing morphology

Glaucoma is a leading cause of blindness in the world. A proven condition for preventing the progression of glaucomatous optic neuropathy is to reduce intraocular pressure. Therapy begins with local hypotensive drugs; if they are ineffective, laser treatment or surgery is used. However, hypotensive...

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Main Authors: N. S. Izmailova, S. Yu. Petrov, A. D. Dzebisova
Format: Article
Language:Russian
Published: Real Time Ltd 2024-12-01
Series:Российский офтальмологический журнал
Subjects:
Online Access:https://roj.igb.ru/jour/article/view/1633
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author N. S. Izmailova
S. Yu. Petrov
A. D. Dzebisova
author_facet N. S. Izmailova
S. Yu. Petrov
A. D. Dzebisova
author_sort N. S. Izmailova
collection DOAJ
description Glaucoma is a leading cause of blindness in the world. A proven condition for preventing the progression of glaucomatous optic neuropathy is to reduce intraocular pressure. Therapy begins with local hypotensive drugs; if they are ineffective, laser treatment or surgery is used. However, hypotensive intervention does not guarantee a stable hypotensive effect. Wound healing is a complex physiological dynamic process that is necessary to maintain homeostasis in the body. This process includes three interrelated phases: inflammation, fibroplasia, and remodulation (maturation) of the scar. Thе review presents various cellular mechanisms involved in the regulation of these processes and factors that contribute to excessive scarring. The review presents various cellular mechanisms involved in the regulation of these processes and contributing to excessive scarring. Current knowledge about the key factors of pathomorphological processes occurring in the filtration zone is intended to stimulate the development of new methods for prolonging the effect of filtering surgery.
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series Российский офтальмологический журнал
spelling doaj-art-1e49b9b056314c9baab5b80d1b42eba32025-08-03T19:22:37ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602024-12-0117411612010.21516/2072-0076-2024-17-4-116-120747Wound healing in glaucoma surgery. Part 1. Wound healing morphologyN. S. Izmailova0S. Yu. Petrov1A. D. Dzebisova2Helmholtz National Medical Research Center of Eye DiseasesHelmholtz National Medical Research Center of Eye DiseasesHelmholtz National Medical Research Center of Eye DiseasesGlaucoma is a leading cause of blindness in the world. A proven condition for preventing the progression of glaucomatous optic neuropathy is to reduce intraocular pressure. Therapy begins with local hypotensive drugs; if they are ineffective, laser treatment or surgery is used. However, hypotensive intervention does not guarantee a stable hypotensive effect. Wound healing is a complex physiological dynamic process that is necessary to maintain homeostasis in the body. This process includes three interrelated phases: inflammation, fibroplasia, and remodulation (maturation) of the scar. Thе review presents various cellular mechanisms involved in the regulation of these processes and factors that contribute to excessive scarring. The review presents various cellular mechanisms involved in the regulation of these processes and contributing to excessive scarring. Current knowledge about the key factors of pathomorphological processes occurring in the filtration zone is intended to stimulate the development of new methods for prolonging the effect of filtering surgery.https://roj.igb.ru/jour/article/view/1633glaucomawound healingmorphology, risk factors
spellingShingle N. S. Izmailova
S. Yu. Petrov
A. D. Dzebisova
Wound healing in glaucoma surgery. Part 1. Wound healing morphology
Российский офтальмологический журнал
glaucoma
wound healing
morphology, risk factors
title Wound healing in glaucoma surgery. Part 1. Wound healing morphology
title_full Wound healing in glaucoma surgery. Part 1. Wound healing morphology
title_fullStr Wound healing in glaucoma surgery. Part 1. Wound healing morphology
title_full_unstemmed Wound healing in glaucoma surgery. Part 1. Wound healing morphology
title_short Wound healing in glaucoma surgery. Part 1. Wound healing morphology
title_sort wound healing in glaucoma surgery part 1 wound healing morphology
topic glaucoma
wound healing
morphology, risk factors
url https://roj.igb.ru/jour/article/view/1633
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AT addzebisova woundhealinginglaucomasurgerypart1woundhealingmorphology