A Central Role for Troponin C Amino-Terminal α-Helix in Vertebrate Thin Filament Ca<sup>2+</sup>-Activation
Troponin C (TnC) is the Ca<sup>2+</sup>-sensing subunit of troponin that is responsible for activating thin filaments in striated muscle, and, in turn, for regulating the systolic and diastolic contractile function of cardiac muscle. The secondary structure of vertebrate TnC is mainly co...
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Main Authors: | Yun Shi, Lauren A. Blackwell, Ryan K. Schroy, B. Max Cleland, Cristina M. Risi, Michelle S. Parvatiyar, Jose R. Pinto, Vitold E. Galkin, P. Bryant Chase |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2025-04-01
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Series: | Physchem |
Subjects: | |
Online Access: | https://www.mdpi.com/2673-7167/5/2/16 |
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