Indoleamine-2,3-dioxygenase: An important controller in maintaining mesenchymal stem cell-mediated immunomodulatory homeostasis

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Indoleamine-2,3-dioxygenase: An important controller in maintaining mesenchymal stem cell-mediated immunomodulatory homeostasis

Mesenchymal stem cells (MSCs) have been widely used in the treatment of various autoimmune and inflammation-related diseases due to their potent immunomodulatory properties. Several studies have demonstrated that MSC-mediated immunomodulation is complex and bidirectional, with the in vivo microenvir...

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Bibliographic Details
Main Authors:	Yufei Hui, Xue Jiao, Li Yang, Dejin Lu, Yanbo Han, Wen Yang, Yanli Cao, Yuxi Miao, Shiqiang Gong, Minjie Wei
Format:	Article
Language:	English
Published:	Elsevier 2025-07-01
Series:	Acta Pharmaceutica Sinica B
Subjects:	Mesenchymal stem cells (MSCs) Indoleamine-2,3-dioxygenase (IDO) Immunomodulatory Plasticity Inflammation Tryptophan (Trp)
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211383525002849
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