Celebrex in treatment of joint diseases in patients with risk factors of gastropathy and cardiovascular palhalodydevelopment
Literature digest is presented concerning to gastrointestinal and cardiovascular safety of selective COX- 2 inhibitors including results of Russian clinico-endoscopic study of celebrex efficacy and tolerability in osteoarthritis (OA). Celebrex was administered to the pts with risk factors of gastroi...
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| Format: | Article |
| Language: | Russian |
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IMA PRESS LLC
2004-02-01
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| Series: | Научно-практическая ревматология |
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| Online Access: | https://rsp.mediar-press.net/rsp/article/view/1234 |
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| _version_ | 1839568662909943808 |
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| author | N. V. Chichasova G R Imametdinova E L Nassonov |
| author_facet | N. V. Chichasova G R Imametdinova E L Nassonov |
| author_sort | N. V. Chichasova |
| collection | DOAJ |
| description | Literature digest is presented concerning to gastrointestinal and cardiovascular safety of selective COX- 2 inhibitors including results of Russian clinico-endoscopic study of celebrex efficacy and tolerability in osteoarthritis (OA). Celebrex was administered to the pts with risk factors of gastrointestinal and cardiovascular adverse events development. Results of longstanding treatment of pts with OA and rheumatoid arthritis (RA) which were prospectively followed up are presented. Celebrex was shown to have high efficacy (about 90% responders) and good tolerability independently on age, duration of treatment and daily dose. Esophagogastroduodenoscopy revealed ulcer development in 4% pts with OA with history of ulcer and in 2,4% pts with RA. |
| format | Article |
| id | doaj-art-1d8d6afeb6eb4a30b07baf5186cb15ae |
| institution | Matheson Library |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| publishDate | 2004-02-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj-art-1d8d6afeb6eb4a30b07baf5186cb15ae2025-08-04T17:03:46ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922004-02-01421394210.14412/1995-4484-2004-13811174Celebrex in treatment of joint diseases in patients with risk factors of gastropathy and cardiovascular palhalodydevelopmentN. V. ChichasovaG R ImametdinovaE L NassonovLiterature digest is presented concerning to gastrointestinal and cardiovascular safety of selective COX- 2 inhibitors including results of Russian clinico-endoscopic study of celebrex efficacy and tolerability in osteoarthritis (OA). Celebrex was administered to the pts with risk factors of gastrointestinal and cardiovascular adverse events development. Results of longstanding treatment of pts with OA and rheumatoid arthritis (RA) which were prospectively followed up are presented. Celebrex was shown to have high efficacy (about 90% responders) and good tolerability independently on age, duration of treatment and daily dose. Esophagogastroduodenoscopy revealed ulcer development in 4% pts with OA with history of ulcer and in 2,4% pts with RA.https://rsp.mediar-press.net/rsp/article/view/1234celebrexrheumatoid arthritisosteoarthritisrisk factors of complications |
| spellingShingle | N. V. Chichasova G R Imametdinova E L Nassonov Celebrex in treatment of joint diseases in patients with risk factors of gastropathy and cardiovascular palhalodydevelopment Научно-практическая ревматология celebrex rheumatoid arthritis osteoarthritis risk factors of complications |
| title | Celebrex in treatment of joint diseases in patients with risk factors of gastropathy and cardiovascular palhalodydevelopment |
| title_full | Celebrex in treatment of joint diseases in patients with risk factors of gastropathy and cardiovascular palhalodydevelopment |
| title_fullStr | Celebrex in treatment of joint diseases in patients with risk factors of gastropathy and cardiovascular palhalodydevelopment |
| title_full_unstemmed | Celebrex in treatment of joint diseases in patients with risk factors of gastropathy and cardiovascular palhalodydevelopment |
| title_short | Celebrex in treatment of joint diseases in patients with risk factors of gastropathy and cardiovascular palhalodydevelopment |
| title_sort | celebrex in treatment of joint diseases in patients with risk factors of gastropathy and cardiovascular palhalodydevelopment |
| topic | celebrex rheumatoid arthritis osteoarthritis risk factors of complications |
| url | https://rsp.mediar-press.net/rsp/article/view/1234 |
| work_keys_str_mv | AT nvchichasova celebrexintreatmentofjointdiseasesinpatientswithriskfactorsofgastropathyandcardiovascularpalhalodydevelopment AT grimametdinova celebrexintreatmentofjointdiseasesinpatientswithriskfactorsofgastropathyandcardiovascularpalhalodydevelopment AT elnassonov celebrexintreatmentofjointdiseasesinpatientswithriskfactorsofgastropathyandcardiovascularpalhalodydevelopment |