Immunohistochemical parameters in prognosis of the locally advanced cervical cancer

This review estimates immunohistochemical parameters reflecting apoptotic, proliferative activities, participating in angiogenesis and defining biological behavior of the tumor because treatment outcomes of locally advanced cervical cancer remain poor. Disease recurrences occur within the first two...

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Main Authors: O. N. Churuksaeva, L. A. Kolomiyets, O. V. Savenkova, V. V. Nedosekov
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Опухоли женской репродуктивной системы
Subjects:
Online Access:https://ojrs.abvpress.ru/ojrs/article/view/127
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author O. N. Churuksaeva
L. A. Kolomiyets
O. V. Savenkova
V. V. Nedosekov
author_facet O. N. Churuksaeva
L. A. Kolomiyets
O. V. Savenkova
V. V. Nedosekov
author_sort O. N. Churuksaeva
collection DOAJ
description This review estimates immunohistochemical parameters reflecting apoptotic, proliferative activities, participating in angiogenesis and defining biological behavior of the tumor because treatment outcomes of locally advanced cervical cancer remain poor. Disease recurrences occur within the first two years after treatment in half of the patients. At the same time, many issues concerning the role of various indices of tumor growth as prognostic factors are controversial. Therefore, the study of histological patterns and molecular-biological characteristics of the tumor and their influence on short- and long-term treatment results are of great importance. The study of biological markers for locally advanced cervical cancer will allow physicians to understand tumor status, to predict the disease and to individualize treatment plan.
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series Опухоли женской репродуктивной системы
spelling doaj-art-1d2a9d6d303746bb8c9b137d23c4a1c72025-08-04T14:33:37ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-07-0103-412613210.17650/1994-4098-2012-0-3-4-126-132143Immunohistochemical parameters in prognosis of the locally advanced cervical cancerO. N. Churuksaeva0L. A. Kolomiyets1O. V. Savenkova2V. V. Nedosekov3Cancer Research Institute of SiberianBranch of the Russian Academy of Medical Sciences, TomskCancer Research Institute of SiberianBranch of the Russian Academy of Medical Sciences, Tomsk Siberian state medical university, TomskCancer Research Institute of SiberianBranch of the Russian Academy of Medical Sciences, TomskCancer Research Institute of SiberianBranch of the Russian Academy of Medical Sciences, TomskThis review estimates immunohistochemical parameters reflecting apoptotic, proliferative activities, participating in angiogenesis and defining biological behavior of the tumor because treatment outcomes of locally advanced cervical cancer remain poor. Disease recurrences occur within the first two years after treatment in half of the patients. At the same time, many issues concerning the role of various indices of tumor growth as prognostic factors are controversial. Therefore, the study of histological patterns and molecular-biological characteristics of the tumor and their influence on short- and long-term treatment results are of great importance. The study of biological markers for locally advanced cervical cancer will allow physicians to understand tumor status, to predict the disease and to individualize treatment plan.https://ojrs.abvpress.ru/ojrs/article/view/127cervical cancerimmunohistochemical parametersprognostic factors
spellingShingle O. N. Churuksaeva
L. A. Kolomiyets
O. V. Savenkova
V. V. Nedosekov
Immunohistochemical parameters in prognosis of the locally advanced cervical cancer
Опухоли женской репродуктивной системы
cervical cancer
immunohistochemical parameters
prognostic factors
title Immunohistochemical parameters in prognosis of the locally advanced cervical cancer
title_full Immunohistochemical parameters in prognosis of the locally advanced cervical cancer
title_fullStr Immunohistochemical parameters in prognosis of the locally advanced cervical cancer
title_full_unstemmed Immunohistochemical parameters in prognosis of the locally advanced cervical cancer
title_short Immunohistochemical parameters in prognosis of the locally advanced cervical cancer
title_sort immunohistochemical parameters in prognosis of the locally advanced cervical cancer
topic cervical cancer
immunohistochemical parameters
prognostic factors
url https://ojrs.abvpress.ru/ojrs/article/view/127
work_keys_str_mv AT onchuruksaeva immunohistochemicalparametersinprognosisofthelocallyadvancedcervicalcancer
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AT ovsavenkova immunohistochemicalparametersinprognosisofthelocallyadvancedcervicalcancer
AT vvnedosekov immunohistochemicalparametersinprognosisofthelocallyadvancedcervicalcancer