Advancing Anesthesia Care and Challenges by Artificial Intelligence: A Prospective Study based on Systematic Review and Meta-Analysis

Background: AI technologies remain essential in modern perioperative care, where they improve clinical decision outcomes and delivery of anesthesia. Health professionals need additional validation testing to determine the practical implementation of these systems for regular medical practice. This...

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Main Authors: Mostafa Ahmed Abdellah Ahmed, Attiya Razzaq, Amna Batool, Shaheer Nayyar, Mahmood Ahmad Zahid, Muhammad Hussain
Format: Article
Language:English
Published: ziauddin University 2025-07-01
Series:Pakistan Journal of Medicine and Dentistry
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Online Access:https://ojs.zu.edu.pk/pjmd/article/view/3725
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author Mostafa Ahmed Abdellah Ahmed
Attiya Razzaq
Amna Batool
Shaheer Nayyar
Mahmood Ahmad Zahid
Muhammad Hussain
author_facet Mostafa Ahmed Abdellah Ahmed
Attiya Razzaq
Amna Batool
Shaheer Nayyar
Mahmood Ahmad Zahid
Muhammad Hussain
author_sort Mostafa Ahmed Abdellah Ahmed
collection DOAJ
description Background: AI technologies remain essential in modern perioperative care, where they improve clinical decision outcomes and delivery of anesthesia. Health professionals need additional validation testing to determine the practical implementation of these systems for regular medical practice. This study aimed to evaluate the clinical effectiveness and diagnostic accuracy of AI-based tools in anesthesia and perioperative care. Methods: This PRISMA-2020 based review included studies published till May 2025 on AI use in anesthesia and perioperative care with clinical outcomes. Two reviewers independently extracted data and assessed bias (Cochrane for RCTs, NOS for observational). Meta-analysis was done using RevMan 5.4.1 under a random-effects inverse-variance model. Results were reported as SMDs for clinical effectiveness and ORs for diagnostic accuracy. Heterogeneity (I²), subgroup, and sensitivity analyses were also performed. Results: Seven research studies (5 as randomized controlled trials, 2 as observational ones) with 1,821 patients were found on inclusion. Anesthesia was implemented with the use of AI in the prediction of the diagnosis, monitoring of sedation, and facilitation of recovery. There were no significant differences in the outcomes of recovery (SMD: -0.36, 95% CI: -1.20 to 0.49). More diagnostic accuracy was achieved under the influence of AI (OR: 2.12; 95% CI: 1.05 to 4.27). The risk of bias was moderate or low. Discussion: New evidence indicates that AI will transform perioperative care through automated decision support functions and outcome prediction solutions; however, a key limitation is the small number of eligible studies and high variability across clinical settings. Thus, standard evaluation standards and multicenter testing activities are necessary for this potential to become realizable.
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spelling doaj-art-1d201b9d1f7c497dac22e90ce7d8e7152025-07-22T06:00:22Zengziauddin UniversityPakistan Journal of Medicine and Dentistry2313-73712308-25932025-07-0114310.36283/ziun-pjmd14-3/063Advancing Anesthesia Care and Challenges by Artificial Intelligence: A Prospective Study based on Systematic Review and Meta-AnalysisMostafa Ahmed Abdellah Ahmed0Attiya Razzaq1Amna Batool2Shaheer Nayyar3Mahmood Ahmad Zahid4Muhammad Hussain5Frimley Health NHS Foundation TrustGulab Devi Teaching Hospital , Lahore,Pakistan.Fatima Memorial Hospital Lahore , PakistanAllama Iqbal Medical College, Jinnah Hospital Lahore, Pakistan.Sheikh Khalifa Bin Zaid Hospital / CMH Rawalakot Azad Kashmir,Pakistan.University of Florence, Italy. Background: AI technologies remain essential in modern perioperative care, where they improve clinical decision outcomes and delivery of anesthesia. Health professionals need additional validation testing to determine the practical implementation of these systems for regular medical practice. This study aimed to evaluate the clinical effectiveness and diagnostic accuracy of AI-based tools in anesthesia and perioperative care. Methods: This PRISMA-2020 based review included studies published till May 2025 on AI use in anesthesia and perioperative care with clinical outcomes. Two reviewers independently extracted data and assessed bias (Cochrane for RCTs, NOS for observational). Meta-analysis was done using RevMan 5.4.1 under a random-effects inverse-variance model. Results were reported as SMDs for clinical effectiveness and ORs for diagnostic accuracy. Heterogeneity (I²), subgroup, and sensitivity analyses were also performed. Results: Seven research studies (5 as randomized controlled trials, 2 as observational ones) with 1,821 patients were found on inclusion. Anesthesia was implemented with the use of AI in the prediction of the diagnosis, monitoring of sedation, and facilitation of recovery. There were no significant differences in the outcomes of recovery (SMD: -0.36, 95% CI: -1.20 to 0.49). More diagnostic accuracy was achieved under the influence of AI (OR: 2.12; 95% CI: 1.05 to 4.27). The risk of bias was moderate or low. Discussion: New evidence indicates that AI will transform perioperative care through automated decision support functions and outcome prediction solutions; however, a key limitation is the small number of eligible studies and high variability across clinical settings. Thus, standard evaluation standards and multicenter testing activities are necessary for this potential to become realizable. https://ojs.zu.edu.pk/pjmd/article/view/3725Artificial IntelligenceAnesthesiaPerioperative CareClinical Decision Support SystemsMachine Learning
spellingShingle Mostafa Ahmed Abdellah Ahmed
Attiya Razzaq
Amna Batool
Shaheer Nayyar
Mahmood Ahmad Zahid
Muhammad Hussain
Advancing Anesthesia Care and Challenges by Artificial Intelligence: A Prospective Study based on Systematic Review and Meta-Analysis
Pakistan Journal of Medicine and Dentistry
Artificial Intelligence
Anesthesia
Perioperative Care
Clinical Decision Support Systems
Machine Learning
title Advancing Anesthesia Care and Challenges by Artificial Intelligence: A Prospective Study based on Systematic Review and Meta-Analysis
title_full Advancing Anesthesia Care and Challenges by Artificial Intelligence: A Prospective Study based on Systematic Review and Meta-Analysis
title_fullStr Advancing Anesthesia Care and Challenges by Artificial Intelligence: A Prospective Study based on Systematic Review and Meta-Analysis
title_full_unstemmed Advancing Anesthesia Care and Challenges by Artificial Intelligence: A Prospective Study based on Systematic Review and Meta-Analysis
title_short Advancing Anesthesia Care and Challenges by Artificial Intelligence: A Prospective Study based on Systematic Review and Meta-Analysis
title_sort advancing anesthesia care and challenges by artificial intelligence a prospective study based on systematic review and meta analysis
topic Artificial Intelligence
Anesthesia
Perioperative Care
Clinical Decision Support Systems
Machine Learning
url https://ojs.zu.edu.pk/pjmd/article/view/3725
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