Analysis of cerebrospinal fluid tumor-derived DNA to obviate biopsy of IDH-mutant brainstem glioma in an adult

Adult brainstem gliomas are rare and present unique diagnostic and therapeutic challenges due to their critical location and limited biopsy feasibility. Molecular profiling of tumor-derived DNA (t-DNA) isolated from cerebrospinal fluid (CSF) is emerging as a minimally invasive alternative for charac...

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Bibliographic Details
Main Authors: Michael Youssef, Alexandra Larson, Vindhya Udhane, Kala F. Schilter, Qian Nie, Honey V. Reddi
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:The Journal of Liquid Biopsy
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Online Access:http://www.sciencedirect.com/science/article/pii/S2950195425000347
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