JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: CLINICAL FEATURES AND CURRENT DIAGNOSTIC APPROACHES

Systemic lupus erythematosus (SLE) is an autoimmune disease with various organs and systems involved in the pathological process, with an unpredictable course, a risk for life-threatening conditions, and an onset from childhood through adolescence in 10–20% of cases. The onset of SLE prior to adult...

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Main Authors: M. I. Kaleda, I. P. Nikishina
Format: Article
Language:Russian
Published: IMA PRESS LLC 2017-10-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/2436
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author M. I. Kaleda
I. P. Nikishina
author_facet M. I. Kaleda
I. P. Nikishina
author_sort M. I. Kaleda
collection DOAJ
description Systemic lupus erythematosus (SLE) is an autoimmune disease with various organs and systems involved in the pathological process, with an unpredictable course, a risk for life-threatening conditions, and an onset from childhood through adolescence in 10–20% of cases. The onset of SLE prior to adult age affects its clinical manifestations, course, and prognosis. Based on the data available in the literature, the paper analyzes the features of the onset and clinical presentations of SLE in children and adolescents and discusses the aspects of verifying its diagnosis, by taking into account the need to use early effective personalized therapy and to improve prognosis.
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series Научно-практическая ревматология
spelling doaj-art-1b9fdeacf02e4f069da8159c47acb0e22025-08-04T17:03:57ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922017-10-0155552653510.14412/1995-4484-2017-526-5352272JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: CLINICAL FEATURES AND CURRENT DIAGNOSTIC APPROACHESM. I. Kaleda0I. P. Nikishina1V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologySystemic lupus erythematosus (SLE) is an autoimmune disease with various organs and systems involved in the pathological process, with an unpredictable course, a risk for life-threatening conditions, and an onset from childhood through adolescence in 10–20% of cases. The onset of SLE prior to adult age affects its clinical manifestations, course, and prognosis. Based on the data available in the literature, the paper analyzes the features of the onset and clinical presentations of SLE in children and adolescents and discusses the aspects of verifying its diagnosis, by taking into account the need to use early effective personalized therapy and to improve prognosis.https://rsp.mediar-press.net/rsp/article/view/2436juvenile-onset systemic systemic lupus erythematosusdiagnostic criteria for systemic lupus erythematosus in childrenchildhood and young age
spellingShingle M. I. Kaleda
I. P. Nikishina
JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: CLINICAL FEATURES AND CURRENT DIAGNOSTIC APPROACHES
Научно-практическая ревматология
juvenile-onset systemic systemic lupus erythematosus
diagnostic criteria for systemic lupus erythematosus in children
childhood and young age
title JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: CLINICAL FEATURES AND CURRENT DIAGNOSTIC APPROACHES
title_full JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: CLINICAL FEATURES AND CURRENT DIAGNOSTIC APPROACHES
title_fullStr JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: CLINICAL FEATURES AND CURRENT DIAGNOSTIC APPROACHES
title_full_unstemmed JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: CLINICAL FEATURES AND CURRENT DIAGNOSTIC APPROACHES
title_short JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: CLINICAL FEATURES AND CURRENT DIAGNOSTIC APPROACHES
title_sort juvenile onset systemic lupus erythematosus clinical features and current diagnostic approaches
topic juvenile-onset systemic systemic lupus erythematosus
diagnostic criteria for systemic lupus erythematosus in children
childhood and young age
url https://rsp.mediar-press.net/rsp/article/view/2436
work_keys_str_mv AT mikaleda juvenileonsetsystemiclupuserythematosusclinicalfeaturesandcurrentdiagnosticapproaches
AT ipnikishina juvenileonsetsystemiclupuserythematosusclinicalfeaturesandcurrentdiagnosticapproaches