Itpka depletion implicates defects in anterior neural development of Xenopus laevis

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Itpka depletion implicates defects in anterior neural development of Xenopus laevis

Inositol 1,4,5-trisphosphate 3-kinase A (Itpka) is a neuronal isoform of the ITPK family that regulates both actin dynamics and calcium signaling. While itpka deficiency in adult mice mainly results in central nervous system phenotypes, its contribution to early development remains unclear. To study...

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Bibliographic Details
Main Authors:	Ernestine Saumweber, Marie-Christine Becker, Sophie Kunkel, Jana Welke, Sandra Schott, Christian Vizinho-Vieira, Selina Faoual, Michael J. Schmeisser, Susanne J. Kühl
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	ITPKA anterior neural development Xenopus laevis disease modeling embryogenesis
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1610183/full
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