Role of Desmoglein Autoantibody in the Diagnosis of Pemphigus Vulgaris: A Case Report
Pemphigus vulgaris (PV) is a group of autoimmune diseases that cause abnormalities in the form of lesions or blisters on the skin and mucous membranes. It often presents diagnostic challenges due to its varied clinical manifestations. Accurate diagnosis and treatment are essential to reduce mortali...
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| Format: | Article |
| Language: | English |
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Interna Publishing
2025-07-01
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| Series: | Acta Medica Indonesiana |
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| Online Access: | http://www.actamedindones.org/index.php/ijim/article/view/2837 |
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| author | Diane Lukito Setiawan Munawaroh Fitriah Awalia Awalia |
| author_facet | Diane Lukito Setiawan Munawaroh Fitriah Awalia Awalia |
| author_sort | Diane Lukito Setiawan |
| collection | DOAJ |
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Pemphigus vulgaris (PV) is a group of autoimmune diseases that cause abnormalities in the form of lesions or blisters on the skin and mucous membranes. It often presents diagnostic challenges due to its varied clinical manifestations. Accurate diagnosis and treatment are essential to reduce mortality in patients with PV. Traditional diagnostic methods, such as histopathology and direct immunofluorescence, may not always provide conclusive results, especially if the patient does not have an intact bulla. Our report emphasizes the role of desmoglein autoantibody testing using enzyme-linked immunosorbent assay to confirm the diagnosis, allowing for prompt and targeted therapeutic interventions.
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| format | Article |
| id | doaj-art-1b90e5a68ee64f1d95e8d6a06ffe5bc0 |
| institution | Matheson Library |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-1b90e5a68ee64f1d95e8d6a06ffe5bc02025-07-14T06:59:53ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322025-07-01572Role of Desmoglein Autoantibody in the Diagnosis of Pemphigus Vulgaris: A Case ReportDiane Lukito Setiawan0Munawaroh Fitriah1Awalia Awalia2Clinical Pathology Sub-Specialization Program, Department of Clinical Pathology, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo Hospital, Surabaya, Indonesia.Department of Clinical Pathology, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo Hospital, Surabaya, IndonesiaDepartment of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo Hospital, Surabaya, Indonesia Pemphigus vulgaris (PV) is a group of autoimmune diseases that cause abnormalities in the form of lesions or blisters on the skin and mucous membranes. It often presents diagnostic challenges due to its varied clinical manifestations. Accurate diagnosis and treatment are essential to reduce mortality in patients with PV. Traditional diagnostic methods, such as histopathology and direct immunofluorescence, may not always provide conclusive results, especially if the patient does not have an intact bulla. Our report emphasizes the role of desmoglein autoantibody testing using enzyme-linked immunosorbent assay to confirm the diagnosis, allowing for prompt and targeted therapeutic interventions. http://www.actamedindones.org/index.php/ijim/article/view/2837Pemphigus vulgarisautoantibodydesmoglein |
| spellingShingle | Diane Lukito Setiawan Munawaroh Fitriah Awalia Awalia Role of Desmoglein Autoantibody in the Diagnosis of Pemphigus Vulgaris: A Case Report Acta Medica Indonesiana Pemphigus vulgaris autoantibody desmoglein |
| title | Role of Desmoglein Autoantibody in the Diagnosis of Pemphigus Vulgaris: A Case Report |
| title_full | Role of Desmoglein Autoantibody in the Diagnosis of Pemphigus Vulgaris: A Case Report |
| title_fullStr | Role of Desmoglein Autoantibody in the Diagnosis of Pemphigus Vulgaris: A Case Report |
| title_full_unstemmed | Role of Desmoglein Autoantibody in the Diagnosis of Pemphigus Vulgaris: A Case Report |
| title_short | Role of Desmoglein Autoantibody in the Diagnosis of Pemphigus Vulgaris: A Case Report |
| title_sort | role of desmoglein autoantibody in the diagnosis of pemphigus vulgaris a case report |
| topic | Pemphigus vulgaris autoantibody desmoglein |
| url | http://www.actamedindones.org/index.php/ijim/article/view/2837 |
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