Selective correction of haemostatic defects in children with acute leukemia and malignant neoplasms
Treatment of children with acute leukemia or other malignant neoplasm can be complicated with bleeding, caused by decreased vitamin K-dependent coagulations factors. Administration of prothrombin complex concentrate seems more convenient than transfusion of fresh frozen plasma with regard to volume...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2022-11-01
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| Series: | Онкогематология |
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| Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/782 |
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| _version_ | 1839574399414435840 |
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| author | V. V. Dmitriev I. A. Dunaev |
| author_facet | V. V. Dmitriev I. A. Dunaev |
| author_sort | V. V. Dmitriev |
| collection | DOAJ |
| description | Treatment of children with acute leukemia or other malignant neoplasm can be complicated with bleeding, caused by decreased vitamin K-dependent coagulations factors. Administration of prothrombin complex concentrate seems more convenient than transfusion of fresh frozen plasma with regard to volume overload and speed of administration. Recombinant rVIIa has been successfully used in patients with uncontrolled bleeding during surgery, including patients with thrombocytopenia. |
| format | Article |
| id | doaj-art-1b2ba60d8c744059af1df1d44f6ebe0b |
| institution | Matheson Library |
| issn | 1818-8346 2413-4023 |
| language | Russian |
| publishDate | 2022-11-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Онкогематология |
| spelling | doaj-art-1b2ba60d8c744059af1df1d44f6ebe0b2025-08-04T13:57:53ZrusABV-pressОнкогематология1818-83462413-40232022-11-0104222610.17650/1818-8346-2009-0-4-22-26660Selective correction of haemostatic defects in children with acute leukemia and malignant neoplasmsV. V. Dmitriev0I. A. Dunaev1Republic Centre for Paediatric Oncology and HaematologyRepublic Centre for Paediatric Oncology and HaematologyTreatment of children with acute leukemia or other malignant neoplasm can be complicated with bleeding, caused by decreased vitamin K-dependent coagulations factors. Administration of prothrombin complex concentrate seems more convenient than transfusion of fresh frozen plasma with regard to volume overload and speed of administration. Recombinant rVIIa has been successfully used in patients with uncontrolled bleeding during surgery, including patients with thrombocytopenia.https://oncohematology.abvpress.ru/ongm/article/view/782childhood acute leukemiamalignant neoplasmhaemostatic defectsbleedingtreatment |
| spellingShingle | V. V. Dmitriev I. A. Dunaev Selective correction of haemostatic defects in children with acute leukemia and malignant neoplasms Онкогематология childhood acute leukemia malignant neoplasm haemostatic defects bleeding treatment |
| title | Selective correction of haemostatic defects in children with acute leukemia and malignant neoplasms |
| title_full | Selective correction of haemostatic defects in children with acute leukemia and malignant neoplasms |
| title_fullStr | Selective correction of haemostatic defects in children with acute leukemia and malignant neoplasms |
| title_full_unstemmed | Selective correction of haemostatic defects in children with acute leukemia and malignant neoplasms |
| title_short | Selective correction of haemostatic defects in children with acute leukemia and malignant neoplasms |
| title_sort | selective correction of haemostatic defects in children with acute leukemia and malignant neoplasms |
| topic | childhood acute leukemia malignant neoplasm haemostatic defects bleeding treatment |
| url | https://oncohematology.abvpress.ru/ongm/article/view/782 |
| work_keys_str_mv | AT vvdmitriev selectivecorrectionofhaemostaticdefectsinchildrenwithacuteleukemiaandmalignantneoplasms AT iadunaev selectivecorrectionofhaemostaticdefectsinchildrenwithacuteleukemiaandmalignantneoplasms |