Bromfenac (Broksinak) — a new word in the nonsteroidal antiinflamatory drug (literature review)
Eye inflammation can be caused by different factors — allergies, infection, trauma (including surgery). It can have severe complications, last even after elimination the reason and cause the visual impairment as an outcome. Two main classes of anti-inflammatory agents (corticosteroids and nonsteroid...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Ophthalmology Publishing Group
2016-01-01
|
| Series: | Oftalʹmologiâ |
| Subjects: | |
| Online Access: | https://www.ophthalmojournal.com/opht/article/view/272 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1839571206096814080 |
|---|---|
| author | E. A. Spiridonov |
| author_facet | E. A. Spiridonov |
| author_sort | E. A. Spiridonov |
| collection | DOAJ |
| description | Eye inflammation can be caused by different factors — allergies, infection, trauma (including surgery). It can have severe complications, last even after elimination the reason and cause the visual impairment as an outcome. Two main classes of anti-inflammatory agents (corticosteroids and nonsteroidal anti-inflammatory drugs (NSAIDs)) are used for the prevention and relief of the inflammatory process. Along with the fact that corticosteroids are the «gold standard» treatment of inflammation in ophthalmology, they have a number of serious side effects such as increasing of intraocular pressure and the risk of developing glaucoma, cataracts, activation of bacterial, viral infection and herpes. The positive effects of NSAIDs in comparison with corticosteroids are stable intraocular pressure (IOP), analgesic effect and reduce the risk of secondary infection. The three classes of NSADs are currently used in ophthalmology. They are phenylacetic acid (diclofenac and bromfenac nepafenak), indole acetic acid (indomethacin) and geteroariluksunoy acid (ketorolac). The last synthesized NSAIDs for ophthalmology are amfenac and bromfenac. Bromfenac is effective for the relief of the inflammatory symptoms of and fully complies with the requirements for the ideal anti-inflammatory drugs such as good a penetration ability, creating a sufficient concentration inside the eye, the activity of cyclooxygenase, inhibiting the progress of macular edema, a good analgesic effect, minimal toxicity, comfort of use patients. Bromfenac is the only nonsteroidal antiinflammatory drugs, which is applied once a day and has a pronounced anti-inflammatory action. |
| format | Article |
| id | doaj-art-1b0ecd3fd93949f48419d08f9b1081b9 |
| institution | Matheson Library |
| issn | 1816-5095 2500-0845 |
| language | Russian |
| publishDate | 2016-01-01 |
| publisher | Ophthalmology Publishing Group |
| record_format | Article |
| series | Oftalʹmologiâ |
| spelling | doaj-art-1b0ecd3fd93949f48419d08f9b1081b92025-08-04T14:32:18ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452016-01-01124182610.18008/1816-5095-2015-4-18-26262Bromfenac (Broksinak) — a new word in the nonsteroidal antiinflamatory drug (literature review)E. A. Spiridonov0State Budget Organization of Healthcare «Samara Regional Clinical Ophthalmologic Hospital named T.I. Eroshevsky»Eye inflammation can be caused by different factors — allergies, infection, trauma (including surgery). It can have severe complications, last even after elimination the reason and cause the visual impairment as an outcome. Two main classes of anti-inflammatory agents (corticosteroids and nonsteroidal anti-inflammatory drugs (NSAIDs)) are used for the prevention and relief of the inflammatory process. Along with the fact that corticosteroids are the «gold standard» treatment of inflammation in ophthalmology, they have a number of serious side effects such as increasing of intraocular pressure and the risk of developing glaucoma, cataracts, activation of bacterial, viral infection and herpes. The positive effects of NSAIDs in comparison with corticosteroids are stable intraocular pressure (IOP), analgesic effect and reduce the risk of secondary infection. The three classes of NSADs are currently used in ophthalmology. They are phenylacetic acid (diclofenac and bromfenac nepafenak), indole acetic acid (indomethacin) and geteroariluksunoy acid (ketorolac). The last synthesized NSAIDs for ophthalmology are amfenac and bromfenac. Bromfenac is effective for the relief of the inflammatory symptoms of and fully complies with the requirements for the ideal anti-inflammatory drugs such as good a penetration ability, creating a sufficient concentration inside the eye, the activity of cyclooxygenase, inhibiting the progress of macular edema, a good analgesic effect, minimal toxicity, comfort of use patients. Bromfenac is the only nonsteroidal antiinflammatory drugs, which is applied once a day and has a pronounced anti-inflammatory action.https://www.ophthalmojournal.com/opht/article/view/272eye inflammationcorticosteroidsnon-hormonal anti-inflammatory agentsbromfenac |
| spellingShingle | E. A. Spiridonov Bromfenac (Broksinak) — a new word in the nonsteroidal antiinflamatory drug (literature review) Oftalʹmologiâ eye inflammation corticosteroids non-hormonal anti-inflammatory agents bromfenac |
| title | Bromfenac (Broksinak) — a new word in the nonsteroidal antiinflamatory drug (literature review) |
| title_full | Bromfenac (Broksinak) — a new word in the nonsteroidal antiinflamatory drug (literature review) |
| title_fullStr | Bromfenac (Broksinak) — a new word in the nonsteroidal antiinflamatory drug (literature review) |
| title_full_unstemmed | Bromfenac (Broksinak) — a new word in the nonsteroidal antiinflamatory drug (literature review) |
| title_short | Bromfenac (Broksinak) — a new word in the nonsteroidal antiinflamatory drug (literature review) |
| title_sort | bromfenac broksinak a new word in the nonsteroidal antiinflamatory drug literature review |
| topic | eye inflammation corticosteroids non-hormonal anti-inflammatory agents bromfenac |
| url | https://www.ophthalmojournal.com/opht/article/view/272 |
| work_keys_str_mv | AT easpiridonov bromfenacbroksinakanewwordinthenonsteroidalantiinflamatorydrugliteraturereview |