The dual role of nuclear factor erythroid 2-related factor 2 in hepatocellular carcinoma: mechanisms, clinical relevance, and therapeutic opportunities
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a pivotal regulator of cellular redox balance and detoxification, critical for maintaining hepatocyte homeostasis. However, its dysregulation has emerged as a key driver in hepatocellular carcinoma (HCC), the most prevalent form of liver cancer....
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Main Authors: | Houhong Wang, Shang Bian |
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Format: | Article |
Language: | English |
Published: |
Open Exploration
2025-07-01
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Series: | Exploration of Drug Science |
Subjects: | |
Online Access: | https://www.explorationpub.com/uploads/Article/A1008119/1008119.pdf |
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