Multi-omics technology reveals the changes in gut microbiota to stimulate aromatic amino acid metabolism in children with allergic rhinitis and constipation

Multi-omics technology reveals the changes in gut microbiota to stimulate aromatic amino acid metabolism in children with allergic rhinitis and constipation

BackgroundComorbid allergic rhinitis and constipation (ARFC) in children are associated with gut microbiota (GM) dysbiosis and metabolic perturbations; however, the underlying mechanistic interplay remains unclear.ObjectiveThis multi-omics study aimed to characterize GM and fecal metabolomic signatu...

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Bibliographic Details
Main Authors: Chunyan Wang, Haiying Liu, Xiaoli Li, Wei Kong, Hui Wu, Congfu Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Allergy
Subjects:
allergic rhinitis
constipation
gut microbiota
aromatic amino acids
high-throughput absolute quantification
metabolomics
Online Access:https://www.frontiersin.org/articles/10.3389/falgy.2025.1562832/full
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