In Silico Analysis of Immunogenic Epitopes in the VP2 Protein of Canine Parvovirus and Codon Optimization for Multivalent Vaccine Design

In Silico Analysis of Immunogenic Epitopes in the VP2 Protein of Canine Parvovirus and Codon Optimization for Multivalent Vaccine Design

Background: Canine parvovirus (CPV) is one of the major agents of severe viral gastroenteritis in dogs. Although vaccines are available, the emergence of new serotypes and mutations in the VP2 protein can compromise vaccine efficacy. Therefore, identifying both conserved and serotype-specific immuno...

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Bibliographic Details
Main Authors: Hossein Samiei-Abianeh, Mahdi Tat, Masoumeh Bolandian, Seyed Akbar Arianzad, Jafar Salimian
Format: Article
Language:English
Published: Bushehr University of Medical Sciences 2025-07-01
Series:Iranian South Medical Journal
Subjects:
bioinformatics
parvovirus
recombinant protein
vp2 gene
vaccine
Online Access:http://ismj.bpums.ac.ir/article-1-2169-en.pdf
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