Native and pegylated forms of L-asparaginase: the assessment of effectiveness and toxicity in acute lymphoblastic leukemia treated with Berlin–Frankfurt–Munster (BFM) protocol
Background. L-asparaginase is an integral part of chemotherapy regimens in treatment of patients with acute lymphoblastic leukemia (ALL). However, the use of L-asparaginase is limited due to wide range of adverse reactions. Our research demonstrates the toxicity effects and treatment results in pati...
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Main Authors: | M. A. Shervashidze, D. S. Smirnova, T. T. Valiev, N. A. Batmanova |
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Format: | Article |
Language: | Russian |
Published: |
ABV-press
2024-12-01
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Series: | Онкогематология |
Subjects: | |
Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/973 |
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