Comparative Efficacy and Safety of Two Different Formulations of Linear Hyaluronic Acid in Patients with Knee Osteoarthritis

QR Code

Comparative Efficacy and Safety of Two Different Formulations of Linear Hyaluronic Acid in Patients with Knee Osteoarthritis

<b>Introduction</b>: Knee osteoarthritis (OA) is defined by articular cartilage loss, increased discomfort, and functional restrictions. Changes in lifestyle, painkillers, intra-articular injections, and, as a last resort, surgery are all part of clinical therapy. In this setting, intra-...

Full description

Saved in:

Bibliographic Details
Main Authors:	Vincenzo Rania, Cristina Vocca, Gianmarco Marcianò, Maria Cristina Caroleo, Lucia Muraca, Emanuele Toraldo, Francesca Greco, Caterina Palleria, Gian Pietro Emerenziani, Luca Gallelli
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Series:	Pharmaceuticals
Subjects:	hyaluronic acid triple injection linear knee osteoarthritis safety efficacy
Online Access:	https://www.mdpi.com/1424-8247/18/7/1065
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

RUSVISK: DOMESTICALLY DEVELOPED PRODUCT OF HYALURONIC ACID: ASSESSMENT OF EFFICACY AND SAFETY IN EARLY STAGES OF THE KNEE OSTEOARTHRITIS
by: N. V. Vas'kova, et al.
Published: (2014-10-01)

INJECTABLE HYALURONIC ACID DRUGS FOR THE TREATMENT OF KNEE OSTEOARTHRITIS IN THE CONTEXT OF EVIDENCE-BASED MEDICINE
by: A. I. Petukhov, et al.
Published: (2018-05-01)

Comparative effectiveness of intra-articular administration of different drugs of hyaluronic acid with various physico-chemical properties in knee osteoarthritis
by: E. A. Belyaeva, et al.
Published: (2021-12-01)

Efficacy of local injection therapy with hyaluronic acid of different molecular weight in patients with knee osteoarthritis
by: V. E. Bialik, et al.
Published: (2019-05-01)

Comparing the results of knee osteoarthritis treatment with intra-articular injection of steroid (methylprednisolone) and hyaluronic acid
by: Seyyed Reza Aghapour, et al.
Published: (2025-06-01)

INTRAARTICULAR INJECTION OF HYALURONIC ACID AFTER ARTHROSCOPIC LAVAGE OF THE KNEE: LONG-TERM RESULTS
by: Lidia Vladimirovna Luchikhina, et al.
Published: (2013-02-01)

THE PLACE OF HYALURONIC ACID PREPARATIONS IN PATIENTS WITH DIFFERENT PHENOTYPES OF KNEE OSTEOARTHRITIS
by: O. V. Teplyakova
Published: (2016-12-01)

Evaluation of the effectiveness of intra-articular administration of highly purified hyaluronic acid in knee osteoarthritis in real clinical practice
by: V. A. Nesterenko, et al.
Published: (2021-10-01)

Efficacy of intra-articular of high molecular weight hyaluronic acid injections in in osteoarthritis of the knee and hip
by: L. I. Alekseeva, et al.
Published: (2021-09-01)

Comparing the efficacy of hyaluronic acid products with various molecular weights as mono and combined with chondroitin sulfate regimens in treatment of patients with stage I–III knee osteoarthritis
by: V. E. Bialik, et al.
Published: (2020-11-01)

HYALURONIC ACID FORMULATIONS IN OSTEOARTHRITIS: POSSIBILITIES FOR IMPORT SUBSTITUTION
by: A. N. Kalyagin, et al.
Published: (2016-12-01)

The use of highmolecular-weight hyaluronic acid in the treatment of osteoarthritis
by: S. G. Anikin
Published: (2017-03-01)

Criteria for choosing a hyaluronic acid preparation for intra-articular administration in patients of different ages with osteoarthritis of the knee joint
by: D. I. Otvetchikova, et al.
Published: (2022-10-01)

The Use of Platelet-Rich Plasma and Hyaluronic Acid in the Treatment of Knee Osteoarthritis – A Review of Current Clinical Evidence
by: Jan Noskowicz, et al.
Published: (2025-06-01)

Clinical Efficacy and Safety of Two Cycles of Intra-Articular Injection of Porcine Atelocollagen Versus Hyaluronic Acid in Knee Osteoarthritis
by: Yong In, et al.
Published: (2025-06-01)

Effects of Injections of Monocytes, Platelet-Rich Plasma, and Hyaluronic Acid in Adults with Knee Osteoarthritis: An Observational Study
by: Rita Chiaramonte, et al.
Published: (2025-03-01)

Comparative evaluation of the efficacy and safety of intra-articular administration of hyaluronic acid and glucocorticoids in the complex therapy of osteoarthritis
by: L. K. Peshekhonova, et al.
Published: (2023-02-01)

Efficacy of hydrolyzed collagen injections compared to platelet-rich plasma and hyaluronic acid in the treatment of patients with symptomatic knee osteoarthritis: a retrospective clinical study
by: Angel Alberto Heredia Sulbaran, et al.
Published: (2025-07-01)

Use of hyaluronic acid preparations in the combination therapy of osteoarthritis
by: Yu. A. Olyunin
Published: (2016-06-01)

Evaluation of the efficiency and safety of combined therapy with a symptomatic sustained-release drug and hyaluronic acid versus monotherapy with hyaluronic acid in patients with knee osteoarthritis
by: K. A. Berdyugin, et al.
Published: (2020-09-01)

Correction of sunken upper eyelids using the triple plane technique with hyaluronic acid fillers
by: Yun Sik Sung, et al.
Published: (2025-06-01)

Ultraphonophoresis with a hyaluronic acid-containing gel for knee osteoarthritis with periarthritis
by: O. N. Anoshenkova, et al.
Published: (2018-12-01)

Hyaluronic acid preparations in the treatment of osteoarthritis. Synvisk®(Hylan G-F 20): Efficacy and safety
by: Natalia Vladimirovna Chichasova
Published: (2013-12-01)

Hyaluronic Acid: Production Strategies, Gel-Forming Properties, and Advances in Drug Delivery Systems
by: Maciej Grabowski, et al.
Published: (2025-06-01)

Comparison of rheological and viscoelastic properties of hyaluronic acid for intraarticular injections
by: A. P. Prizov, et al.
Published: (2023-04-01)

Efficiency of intra-articular hyaluronic acid therapy in patients with osteoarthritis
by: E. A. Strebkova, et al.
Published: (2019-05-01)

Evaluation of the efficacy of high molecular weight hyaluronic acid with chondroitin sulfate in post-traumatic knee osteoarthritis
by: E. I. Bialik, et al.
Published: (2024-08-01)

Evaluation of the efficacy, tolerability, and safety of intra-articular hyaluronic acid in patients with knee osteoarthritis
by: S. G. Anikin, et al.
Published: (2017-09-01)

The efficacy of platelet-rich plasma preparation protocols in the treatment of osteoarthritis: a network meta-analysis of randomized controlled trials
by: Dongsheng Yu, et al.
Published: (2025-06-01)

Low molecular weight hyaluronates: biological action, efficacy, safety and clinical experience in the treatment of musculoskeletal pain syndromes (literature review and clinical observations)
by: M. A. Strakhov, et al.
Published: (2023-02-01)

Efficacy of Hyaluronic Acid in Radiation Proctitis: A Case Series
by: Marcellus Simadibrata, et al.
Published: (2024-10-01)

Hyaluronic Acid in Immune Response
by: Lech Chrostek, et al.
Published: (2025-07-01)

The 2014 guidelines for the management of osteoarthritis: Place of hyaluronic acid preparations
by: N. V. Chichasova, et al.
Published: (2016-01-01)

Acute Pulmonary Complications Following Cosmetic Hyaluronic Acid Dermal Filler Injections
by: Sin Nee Tan, et al.
Published: (2025-06-01)

Hyaluronic acid preparations in the treatment of osteoarthritis: is it clear to us?
by: A. E. Karateev, et al.
Published: (2018-09-01)

EVALUATION OF THE EFFICIENCY OF COMBINATION THERAPY WITH HYALURONATES IN PATIENTS WITH HIP OSTEOARTHROSIS
by: A G Shusharin, et al.
Published: (2011-06-01)

Comparative effects of intra-articular administration of vitamin C, vitamin D, and hyaluronic acid in an experimental osteoarthritis model in rats
by: T. Sancak, et al.
Published: (2025-07-01)

Efficacy of Hyaluronic Acid Injection for Temporomandibular Joint Disorders with and without Arthrocentesis
by: Twana Hoshyar Saleem
Published: (2025-06-01)

Modern approaches to the treatment of joint pathology: the value of hyaluronic acid
by: M. M. Shamuilova, et al.
Published: (2021-12-01)

Nasal reshaping with hyaluronic acid: technique, risks, and benefits
by: André Campoli Frisina, et al.
Published: (2021-03-01)