3D‐Printed Laminae for Kyphosis in Ankylosing Spondylitis During Pedicle Subtraction Osteotomy

ABSTRACT Objective Ankylosing spondylitis (AS) often presents with spinal kyphosis, and pedicle subtraction osteotomy (PSO) is a common surgical technique for correcting AS‐related kyphosis. However, after PSO, the posterior column lacks rigid bone support, potentially leading to intervertebral disc...

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Main Authors: Yilin Lu, Gao Si, Mingxiao Bai, Yongqiang Wang, Yun Tian, Weishi Li, Miao Yu, Yu Wang
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Orthopaedic Surgery
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Online Access:https://doi.org/10.1111/os.70074
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author Yilin Lu
Gao Si
Mingxiao Bai
Yongqiang Wang
Yun Tian
Weishi Li
Miao Yu
Yu Wang
author_facet Yilin Lu
Gao Si
Mingxiao Bai
Yongqiang Wang
Yun Tian
Weishi Li
Miao Yu
Yu Wang
author_sort Yilin Lu
collection DOAJ
description ABSTRACT Objective Ankylosing spondylitis (AS) often presents with spinal kyphosis, and pedicle subtraction osteotomy (PSO) is a common surgical technique for correcting AS‐related kyphosis. However, after PSO, the posterior column lacks rigid bone support, potentially leading to intervertebral disc mobility and loss of correction. This study aims to introduce a novel 3D‐printed laminae for the treatment of AS‐related kyphosis. Methods This is a retrospective cohort study. A total of 48 patients receiving posterior correction surgeries between December 2021 and January 2022 were included and divided into two groups according to whether they accepted the 3D‐printed laminae. We propose a novel approach using 3D‐printed laminae to enhance posterior column stability and reduce deformity loss. Sixteen patients receiving 3D‐printed laminae and 32 patients who did not receive that device. We collected preoperative and postoperative radiographic parameters, perioperative data, and patient‐reported clinical scores. Statistical analysis involved independent sample t tests or randomization tests for continuous variables and chi‐square tests for categorical variables. Results In the implanted group, kyphosis was corrected from 75.88° preoperatively to 27.06° postoperatively, and in the unimplanted group, from 70.98° to 28.42°. At the last follow‐up, the ΔGK (global kyphosis) was 1.76° in the implanted group and 2.50° in the unimplanted group. PJA was 9.77° in the implanted group and 15.45° in the unimplanted group, showing significant differences. Two patients in the unimplanted group experienced sagittal reconstruction failure. Health‐related quality of life (HRQoL) scores improved in the implanted group, with back pain scores of 2.63 and Oswestry Disability Index (ODI) scores of 13.50. Conclusions Our study introduces a novel 3D‐printed laminae technique for AS‐related kyphosis, aiding in maintaining sagittal balance. Patients reported improved subjective outcomes, including reduced pain and better HRQoL.
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spelling doaj-art-1407185750434369a657b3e65cfb7fc62025-07-02T07:34:59ZengWileyOrthopaedic Surgery1757-78531757-78612025-07-011772038204710.1111/os.700743D‐Printed Laminae for Kyphosis in Ankylosing Spondylitis During Pedicle Subtraction OsteotomyYilin Lu0Gao Si1Mingxiao Bai2Yongqiang Wang3Yun Tian4Weishi Li5Miao Yu6Yu Wang7Department of Orthopaedics Peking University Third Hospital Beijing ChinaDepartment of Orthopaedics Peking University Third Hospital Beijing ChinaDepartment of Orthopaedics Rizhao Hospital of Traditional Chinese Medicine Rizhao ChinaDepartment of Orthopaedics Peking University Third Hospital Beijing ChinaDepartment of Orthopaedics Peking University Third Hospital Beijing ChinaDepartment of Orthopaedics Peking University Third Hospital Beijing ChinaDepartment of Orthopaedics Peking University Third Hospital Beijing ChinaDepartment of Orthopaedics Peking University First Hospital Beijing ChinaABSTRACT Objective Ankylosing spondylitis (AS) often presents with spinal kyphosis, and pedicle subtraction osteotomy (PSO) is a common surgical technique for correcting AS‐related kyphosis. However, after PSO, the posterior column lacks rigid bone support, potentially leading to intervertebral disc mobility and loss of correction. This study aims to introduce a novel 3D‐printed laminae for the treatment of AS‐related kyphosis. Methods This is a retrospective cohort study. A total of 48 patients receiving posterior correction surgeries between December 2021 and January 2022 were included and divided into two groups according to whether they accepted the 3D‐printed laminae. We propose a novel approach using 3D‐printed laminae to enhance posterior column stability and reduce deformity loss. Sixteen patients receiving 3D‐printed laminae and 32 patients who did not receive that device. We collected preoperative and postoperative radiographic parameters, perioperative data, and patient‐reported clinical scores. Statistical analysis involved independent sample t tests or randomization tests for continuous variables and chi‐square tests for categorical variables. Results In the implanted group, kyphosis was corrected from 75.88° preoperatively to 27.06° postoperatively, and in the unimplanted group, from 70.98° to 28.42°. At the last follow‐up, the ΔGK (global kyphosis) was 1.76° in the implanted group and 2.50° in the unimplanted group. PJA was 9.77° in the implanted group and 15.45° in the unimplanted group, showing significant differences. Two patients in the unimplanted group experienced sagittal reconstruction failure. Health‐related quality of life (HRQoL) scores improved in the implanted group, with back pain scores of 2.63 and Oswestry Disability Index (ODI) scores of 13.50. Conclusions Our study introduces a novel 3D‐printed laminae technique for AS‐related kyphosis, aiding in maintaining sagittal balance. Patients reported improved subjective outcomes, including reduced pain and better HRQoL.https://doi.org/10.1111/os.700743D‐printedankylosing spondylitiskyphosispedicle subtraction osteotomy
spellingShingle Yilin Lu
Gao Si
Mingxiao Bai
Yongqiang Wang
Yun Tian
Weishi Li
Miao Yu
Yu Wang
3D‐Printed Laminae for Kyphosis in Ankylosing Spondylitis During Pedicle Subtraction Osteotomy
Orthopaedic Surgery
3D‐printed
ankylosing spondylitis
kyphosis
pedicle subtraction osteotomy
title 3D‐Printed Laminae for Kyphosis in Ankylosing Spondylitis During Pedicle Subtraction Osteotomy
title_full 3D‐Printed Laminae for Kyphosis in Ankylosing Spondylitis During Pedicle Subtraction Osteotomy
title_fullStr 3D‐Printed Laminae for Kyphosis in Ankylosing Spondylitis During Pedicle Subtraction Osteotomy
title_full_unstemmed 3D‐Printed Laminae for Kyphosis in Ankylosing Spondylitis During Pedicle Subtraction Osteotomy
title_short 3D‐Printed Laminae for Kyphosis in Ankylosing Spondylitis During Pedicle Subtraction Osteotomy
title_sort 3d printed laminae for kyphosis in ankylosing spondylitis during pedicle subtraction osteotomy
topic 3D‐printed
ankylosing spondylitis
kyphosis
pedicle subtraction osteotomy
url https://doi.org/10.1111/os.70074
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