RNLS promotes ovarian cancer growth and inhibits ferroptosis via mediating STAT3

RNLS promotes ovarian cancer growth and inhibits ferroptosis via mediating STAT3

IntroductionOvarian cancer (OC) is a lethal malignancy for which there are limited therapeutic options. The role of renalase (RNLS) in cancer progression and ferroptosis regulation remains unclear. This study investigates how RNLS mediates STAT3 to promote OC growth and suppress ferroptosis.MethodsR...

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Bibliographic Details
Main Authors: Liang Lin, Zuolian Xie, Peilin Zhong, Jian Chen, Ning Ma, Ling Li, Li Chen, An Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
ovarian cancer
RNLS
STAT3
PI3K/AKT
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1604377/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1604377/full

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