Proactive process evaluation of precision medicine platforms: a roadmap
Background Precision and genomic medicine have significant potential to improve population health. However, despite rapid technological development and increasing data complexity, practical applications of precision medicine remain limited. There is also a lack of evaluation of unintended consequenc...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2025-07-01
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| Series: | BMJ Health & Care Informatics |
| Online Access: | https://informatics.bmj.com/content/32/1/e101434.full |
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| Summary: | Background Precision and genomic medicine have significant potential to improve population health. However, despite rapid technological development and increasing data complexity, practical applications of precision medicine remain limited. There is also a lack of evaluation of unintended consequences and a failure to use theory-based implementation frameworks to manage risks and ensure sustainability.Methods This work provides a conceptual overview of evaluation challenges related to precision medicine platforms, based on existing literature. It proposes a theory-informed proactive process evaluation framework to guide the development and assessment of these platforms.Results The proposed framework considers infrastructural, socio-organisational and system-level factors. It raises key questions, such as: How will platforms integrate with existing infrastructures? How will they transform care pathways and the delivery of care across settings?Conclusions Rapid technological advances challenge markets and regulatory environments. Agile evaluation approaches are crucial for building a sustainable innovation ecosystem for precision medicine platforms. |
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| ISSN: | 2632-1009 |