Safety and efficacy of bridging radiation therapy prior to CD19 CAR T for non-Hodgkin lymphoma: a systematic review and meta-analysis

Bridging radiation therapy (BRT) is increasingly utilized prior to CART19 in NHL patients. However, its impact on CART19 outcomes is not established. We conducted a systematic review and meta-analysis to estimate the safety and efficacy of BRT prior to CART19 therapy. A comprehensive search was per...

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Main Authors: Mohammad Alhomoud, Rahma Ibrahim, Michelle Demetres, Kai Rejeski, Michael Scordo, Roni Shouval, Tobias Tix, Jeremie Martinet, Michelle Foley, Alexandra Gomez-Arteaga, Tsiporah Shore, Paul Pagnini, Mahmoud Aljurf, Monica L. Guzman, Silvia Formenti, Joachim Yahalom, Koen van Besien, Brandon S. Imber, Zhengming Chen, Samuel Yamshon
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-07-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12169
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