Development and application of a stepwise-assembled modular biomimetic lung chip for analyzing formaldehyde-induced cellular ferroptosis

Development and application of a stepwise-assembled modular biomimetic lung chip for analyzing formaldehyde-induced cellular ferroptosis

Formaldehyde poses a significant threat to human health, yet its toxicity assessment is limited by current detection methods. This study developed a modular biomimetic lung chip which consists of gas concentration gradient generator module and cell culture module, assembled using alignment holes and...

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Bibliographic Details
Main Authors: Siyu Chen, Zezhi Li, Quanping Yan, Chenfeng Hua, Pingping Shang, Kejian Liu, Junwei Zhao, Guangxiang Jin, Xiang Li, Fuwei Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
microfluidic
modular
stepwise-assembled
biomimetic lung chip
formaldehyde
ferroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1570270/full
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