<i>Hamamelis virginiana</i> L. in Skin Care: A Review of Its Pharmacological Properties and Cosmetological Applications
<i>Hamamelis virginiana</i> L. (witch hazel) is a traditionally used medicinal plant, well-known for its dermatological applications. The plant’s bark and leaves contain a rich array of bioactive compounds, including phenolic acids, flavonoids, catechins, proanthocyanidins, and tannins,...
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| Language: | English |
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2025-06-01
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| author | Magdalena Wójciak Wiktoria Pacuła Ireneusz Sowa Marcin Feldo Filip Graczyk Daniel Załuski |
| author_facet | Magdalena Wójciak Wiktoria Pacuła Ireneusz Sowa Marcin Feldo Filip Graczyk Daniel Załuski |
| author_sort | Magdalena Wójciak |
| collection | DOAJ |
| description | <i>Hamamelis virginiana</i> L. (witch hazel) is a traditionally used medicinal plant, well-known for its dermatological applications. The plant’s bark and leaves contain a rich array of bioactive compounds, including phenolic acids, flavonoids, catechins, proanthocyanidins, and tannins, many of which exhibit antimicrobial, anti-inflammatory, antioxidant, and wound-healing properties. These activities have been verified by numerous in vitro and in vivo studies, as well as limited clinical trials. The <i>H. virginiana</i> extracts have demonstrated effectiveness against bacteria, fungi, and some viruses. Moreover, the extracts exert anti-inflammatory effects by modulating cytokine expression and NF-κB signaling, improve skin regeneration, and protect against UV-induced damage and pollution. This review highlights <i>H. virginiana</i> as a complex botanical resource to be used in dermatology and cosmetology and shows that current research offers encouraging results for its future therapeutic use, especially in skin treatment. |
| format | Article |
| id | doaj-art-101fd7afedda4e77bcccfd29cf02b852 |
| institution | Matheson Library |
| issn | 1420-3049 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj-art-101fd7afedda4e77bcccfd29cf02b8522025-07-11T14:40:58ZengMDPI AGMolecules1420-30492025-06-013013274410.3390/molecules30132744<i>Hamamelis virginiana</i> L. in Skin Care: A Review of Its Pharmacological Properties and Cosmetological ApplicationsMagdalena Wójciak0Wiktoria Pacuła1Ireneusz Sowa2Marcin Feldo3Filip Graczyk4Daniel Załuski5Department of Analytical Chemistry, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, PolandDepartment of Analytical Chemistry, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, PolandDepartment of Analytical Chemistry, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, PolandChair and Department of Vascular Surgery and Angiology, Medical University of Lublin, 11 Staszica St., 20-081 Lublin, PolandDepartment of Pharmaceutical Botany and Pharmacognosy, Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University, 9 Marie Curie-Skłodowska Street, 85-094 Bydgoszcz, PolandDepartment of Pharmaceutical Botany and Pharmacognosy, Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University, 9 Marie Curie-Skłodowska Street, 85-094 Bydgoszcz, Poland<i>Hamamelis virginiana</i> L. (witch hazel) is a traditionally used medicinal plant, well-known for its dermatological applications. The plant’s bark and leaves contain a rich array of bioactive compounds, including phenolic acids, flavonoids, catechins, proanthocyanidins, and tannins, many of which exhibit antimicrobial, anti-inflammatory, antioxidant, and wound-healing properties. These activities have been verified by numerous in vitro and in vivo studies, as well as limited clinical trials. The <i>H. virginiana</i> extracts have demonstrated effectiveness against bacteria, fungi, and some viruses. Moreover, the extracts exert anti-inflammatory effects by modulating cytokine expression and NF-κB signaling, improve skin regeneration, and protect against UV-induced damage and pollution. This review highlights <i>H. virginiana</i> as a complex botanical resource to be used in dermatology and cosmetology and shows that current research offers encouraging results for its future therapeutic use, especially in skin treatment.https://www.mdpi.com/1420-3049/30/13/2744witch hazelhamamelitanninbiological activityfibroblastskeratinocytes |
| spellingShingle | Magdalena Wójciak Wiktoria Pacuła Ireneusz Sowa Marcin Feldo Filip Graczyk Daniel Załuski <i>Hamamelis virginiana</i> L. in Skin Care: A Review of Its Pharmacological Properties and Cosmetological Applications Molecules witch hazel hamamelitannin biological activity fibroblasts keratinocytes |
| title | <i>Hamamelis virginiana</i> L. in Skin Care: A Review of Its Pharmacological Properties and Cosmetological Applications |
| title_full | <i>Hamamelis virginiana</i> L. in Skin Care: A Review of Its Pharmacological Properties and Cosmetological Applications |
| title_fullStr | <i>Hamamelis virginiana</i> L. in Skin Care: A Review of Its Pharmacological Properties and Cosmetological Applications |
| title_full_unstemmed | <i>Hamamelis virginiana</i> L. in Skin Care: A Review of Its Pharmacological Properties and Cosmetological Applications |
| title_short | <i>Hamamelis virginiana</i> L. in Skin Care: A Review of Its Pharmacological Properties and Cosmetological Applications |
| title_sort | i hamamelis virginiana i l in skin care a review of its pharmacological properties and cosmetological applications |
| topic | witch hazel hamamelitannin biological activity fibroblasts keratinocytes |
| url | https://www.mdpi.com/1420-3049/30/13/2744 |
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